Long-term disease-free acute myeloblastic leukemia with inv(16) is associated with PCR undetectable CBFβ/MYH11 transcript

Giovanni Martinelli, Emanuela Ottaviani, Nicoletta Testoni, Vittorio Montefusco, Silvia Buonamici, Sante Tura

Research output: Contribution to journalArticle

Abstract

This study investigates the benefits of minimal residual disease in a subset of AML patients with inv(16) by means of non-quantitative detection of CBFβ/MYH11 fusion transcript. We found that CBFβ/MYH11 RT-PCR negativity is associated with cure of disease.

Original languageEnglish
Pages (from-to)552-554
Number of pages3
JournalHaematologica
Volume85
Issue number5
Publication statusPublished - May 2000

ASJC Scopus subject areas

  • Hematology

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