Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging

Alan T. Sheyman, Fabio Scarinci, Amani A. Fawzi, Manjot K. Gill

Research output: Contribution to journalArticle

Abstract

MEK inhibitor chemotherapy, used in various malignancies, has been reported to be associated with serous retinal detachments. This study reports serial multimodal imaging focused primarily on infrared reflectance and spectral-domain optical coherence tomography (SD-OCT) in the monitoring of MEK inhibitor retinal toxicity. The benefit of OCT angiography in understanding the pathophysiology of MEK inhibitor toxicity is also shown.

Original languageEnglish
Pages (from-to)76-77
Number of pages2
JournalOphthalmic surgery, lasers & imaging retina
Volume47
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

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Multimodal Imaging
Mitogen-Activated Protein Kinase Kinases
Optical Coherence Tomography
Retinal Detachment
Angiography
Drug Therapy
Neoplasms

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging. / Sheyman, Alan T.; Scarinci, Fabio; Fawzi, Amani A.; Gill, Manjot K.

In: Ophthalmic surgery, lasers & imaging retina, Vol. 47, No. 1, 01.01.2016, p. 76-77.

Research output: Contribution to journalArticle

Sheyman, Alan T. ; Scarinci, Fabio ; Fawzi, Amani A. ; Gill, Manjot K. / Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging. In: Ophthalmic surgery, lasers & imaging retina. 2016 ; Vol. 47, No. 1. pp. 76-77.
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