Abstract
TPM add-on long-term open-label treatment was evaluated in 76 patients with Partial Refractory Epilepsy over a mean period of 12 months. The mean TPM dosage was 418+168 mg/day. About 30% of patients achieved >50% seizure reduction; 10% of patients were seizure-free. 13 (15%) patients discontinued TPM because of adverse events. Findings from this study show that TPM is ah useful agent for long-term seizure control, with some patients becoming seizure-free.
Translated title of the contribution | Long-term evaluation of the efficacy and tolerability of topiramate as add-on therapy in patients with refractory partial epilepsy |
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Original language | Italian |
Pages (from-to) | 83-84 |
Number of pages | 2 |
Journal | Bollettino - Lega Italiana contro l'Epilessia |
Issue number | 113-114 |
Publication status | Published - 2001 |
ASJC Scopus subject areas
- Clinical Neurology