Abstract
We describe the long-term follow-up of a patient with bilateral striatal necrosis associated with Mycoplasma pneumoniae infection occurred in adolescence. In the literature there are no longitudinal studies of such a rare condition. Our patient, 4 years after the onset of an acute and reversible akinetic-rigid syndrome, showed a severe obsessive-compulsive disorder, cognitive decline, and a neuropsychological profile characterized by signs of deficient executive functioning. The clinical picture that emerged in our patient is suggestive of a frontosubcortical dementia which might be considered a major long-term sequela of the bilateral selective striatal necrosis and consequent dysfunction of frontostriatal connections.
| Original language | English |
|---|---|
| Pages (from-to) | 62-65 |
| Number of pages | 4 |
| Journal | Brain and Development |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2005 |
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Keywords
- Bilateral striatal necrosis
- Frontosubcortical dementia
- Mycoplasma pneumoniae
- Obsessive-compulsive disorder
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
- Neurology
Cite this
Long-term follow-up of an adolescent who had bilateral striatal necrosis secondary to Mycoplasma pneumoniae infection. / Termine, Cristiano; Uggetti, Carla; Veggiotti, Pierangelo; Balottin, Umberto; Rossi, Giorgio; Egitto, Maria Grazia; Lanzi, Giovanni.
In: Brain and Development, Vol. 27, No. 1, 01.2005, p. 62-65.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term follow-up of an adolescent who had bilateral striatal necrosis secondary to Mycoplasma pneumoniae infection
AU - Termine, Cristiano
AU - Uggetti, Carla
AU - Veggiotti, Pierangelo
AU - Balottin, Umberto
AU - Rossi, Giorgio
AU - Egitto, Maria Grazia
AU - Lanzi, Giovanni
PY - 2005/1
Y1 - 2005/1
N2 - We describe the long-term follow-up of a patient with bilateral striatal necrosis associated with Mycoplasma pneumoniae infection occurred in adolescence. In the literature there are no longitudinal studies of such a rare condition. Our patient, 4 years after the onset of an acute and reversible akinetic-rigid syndrome, showed a severe obsessive-compulsive disorder, cognitive decline, and a neuropsychological profile characterized by signs of deficient executive functioning. The clinical picture that emerged in our patient is suggestive of a frontosubcortical dementia which might be considered a major long-term sequela of the bilateral selective striatal necrosis and consequent dysfunction of frontostriatal connections.
AB - We describe the long-term follow-up of a patient with bilateral striatal necrosis associated with Mycoplasma pneumoniae infection occurred in adolescence. In the literature there are no longitudinal studies of such a rare condition. Our patient, 4 years after the onset of an acute and reversible akinetic-rigid syndrome, showed a severe obsessive-compulsive disorder, cognitive decline, and a neuropsychological profile characterized by signs of deficient executive functioning. The clinical picture that emerged in our patient is suggestive of a frontosubcortical dementia which might be considered a major long-term sequela of the bilateral selective striatal necrosis and consequent dysfunction of frontostriatal connections.
KW - Bilateral striatal necrosis
KW - Frontosubcortical dementia
KW - Mycoplasma pneumoniae
KW - Obsessive-compulsive disorder
UR - http://www.scopus.com/inward/record.url?scp=11144232348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11144232348&partnerID=8YFLogxK
U2 - 10.1016/j.braindev.2004.03.010
DO - 10.1016/j.braindev.2004.03.010
M3 - Article
C2 - 15626544
AN - SCOPUS:11144232348
VL - 27
SP - 62
EP - 65
JO - Brain and Development
JF - Brain and Development
SN - 0387-7604
IS - 1
ER -