Long-term follow-up of an adolescent who had bilateral striatal necrosis secondary to Mycoplasma pneumoniae infection

Cristiano Termine, Carla Uggetti, Pierangelo Veggiotti, Umberto Balottin, Giorgio Rossi, Maria Grazia Egitto, Giovanni Lanzi

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the long-term follow-up of a patient with bilateral striatal necrosis associated with Mycoplasma pneumoniae infection occurred in adolescence. In the literature there are no longitudinal studies of such a rare condition. Our patient, 4 years after the onset of an acute and reversible akinetic-rigid syndrome, showed a severe obsessive-compulsive disorder, cognitive decline, and a neuropsychological profile characterized by signs of deficient executive functioning. The clinical picture that emerged in our patient is suggestive of a frontosubcortical dementia which might be considered a major long-term sequela of the bilateral selective striatal necrosis and consequent dysfunction of frontostriatal connections.

Original languageEnglish
Pages (from-to)62-65
Number of pages4
JournalBrain and Development
Volume27
Issue number1
DOIs
Publication statusPublished - Jan 2005

Keywords

  • Bilateral striatal necrosis
  • Frontosubcortical dementia
  • Mycoplasma pneumoniae
  • Obsessive-compulsive disorder

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

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