Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis

Ernesto Bruno, Ehab I. Mohamed, Mohamed Alessandrini, Sabino Russo, Stefania Schiaroli, Antonino De Lorenzo, Alberto Di Girolamo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: The objective of this study was to identify a reproducible clinical parameter for predicting relapses of nasal polyposis after surgery. Methods: Ninety-three patients who had undergone ethmoidectomy of bilateral nasal polyps were followed for 3 years. Nasal polyps were obtained from all patients, and cellular suspensions were analyzed individually using flow cytometry. Based on the percentage of cells in the S phase, we identified three groups of patients (high, medium, and low percentages). Results: A relapse of nasal polyposis was observed in 15.00, 70.00, and 100.00% of patients from the low-, medium-, and high-percentage groups, respectively. Patients suffering relapses had a high percentage of cells in the S phase. Conclusions: We identified two cutoff values for the percentage of cells in the S phase; above the first cutoff, some of the patients suffered relapses; above the second cut-off, all patients suffered relapses.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalAmerican Journal of Rhinology
Volume16
Issue number5
Publication statusPublished - Sep 2002

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Nose
Cell Proliferation
Recurrence
S Phase
Nasal Polyps
Suspensions
Flow Cytometry

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Bruno, E., Mohamed, E. I., Alessandrini, M., Russo, S., Schiaroli, S., De Lorenzo, A., & Di Girolamo, A. (2002). Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis. American Journal of Rhinology, 16(5), 237-241.

Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis. / Bruno, Ernesto; Mohamed, Ehab I.; Alessandrini, Mohamed; Russo, Sabino; Schiaroli, Stefania; De Lorenzo, Antonino; Di Girolamo, Alberto.

In: American Journal of Rhinology, Vol. 16, No. 5, 09.2002, p. 237-241.

Research output: Contribution to journalArticle

Bruno, E, Mohamed, EI, Alessandrini, M, Russo, S, Schiaroli, S, De Lorenzo, A & Di Girolamo, A 2002, 'Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis', American Journal of Rhinology, vol. 16, no. 5, pp. 237-241.
Bruno E, Mohamed EI, Alessandrini M, Russo S, Schiaroli S, De Lorenzo A et al. Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis. American Journal of Rhinology. 2002 Sep;16(5):237-241.
Bruno, Ernesto ; Mohamed, Ehab I. ; Alessandrini, Mohamed ; Russo, Sabino ; Schiaroli, Stefania ; De Lorenzo, Antonino ; Di Girolamo, Alberto. / Long-term follow-up of cellular proliferation as a predictive index for the relapse of nasal polyposis. In: American Journal of Rhinology. 2002 ; Vol. 16, No. 5. pp. 237-241.
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AU - Bruno, Ernesto

AU - Mohamed, Ehab I.

AU - Alessandrini, Mohamed

AU - Russo, Sabino

AU - Schiaroli, Stefania

AU - De Lorenzo, Antonino

AU - Di Girolamo, Alberto

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