Long-term follow-up of dermatitis herpetiformis in children

E. Ermacora, L. Prampolini, G. Tribbia, G. Pezzoli, C. Gelmetti, G. Cucchi, A. Tettamanti, A. Giunta, F. Gianotti

Research output: Contribution to journalArticle

Abstract

Dermatitis herpetiformis was diagnosed in seventy-six children by its clinical features and be detection of granular IgA deposits in the papillary dermis of perilesional skin. Enteric alterations demonstrated by measurements of D-xylose absorption and by small intestinal biopsies were detected in over 90% of all patients. A complete follow-up was obtained for all children who were followed for 3 to 10 years. Treatment with a gluten-free diet alone led to a reversal of the intestinal abnormality in 100% of our children and to the disappearance of cutaneous lesions in 82% of reported cases. This suggests that a complete remission of symptoms can be obtained with a gluten-free diet alone. Dapsone alone is effective therapy for the rash but does not affect the intestinal alterations. Furthermore, the lack of side effects to dietetic therapy for a long period of time makes the diet the treatment of choice in this disease.

Original languageEnglish
Pages (from-to)24-30
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume15
Issue number1
Publication statusPublished - 1986

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Dermatitis Herpetiformis
Gluten-Free Diet
Dapsone
Skin
Dietetics
Xylose
Intestinal Absorption
Therapeutics
Dermis
Exanthema
Immunoglobulin A
Diet
Biopsy

ASJC Scopus subject areas

  • Dermatology

Cite this

Ermacora, E., Prampolini, L., Tribbia, G., Pezzoli, G., Gelmetti, C., Cucchi, G., ... Gianotti, F. (1986). Long-term follow-up of dermatitis herpetiformis in children. Journal of the American Academy of Dermatology, 15(1), 24-30.

Long-term follow-up of dermatitis herpetiformis in children. / Ermacora, E.; Prampolini, L.; Tribbia, G.; Pezzoli, G.; Gelmetti, C.; Cucchi, G.; Tettamanti, A.; Giunta, A.; Gianotti, F.

In: Journal of the American Academy of Dermatology, Vol. 15, No. 1, 1986, p. 24-30.

Research output: Contribution to journalArticle

Ermacora, E, Prampolini, L, Tribbia, G, Pezzoli, G, Gelmetti, C, Cucchi, G, Tettamanti, A, Giunta, A & Gianotti, F 1986, 'Long-term follow-up of dermatitis herpetiformis in children', Journal of the American Academy of Dermatology, vol. 15, no. 1, pp. 24-30.
Ermacora E, Prampolini L, Tribbia G, Pezzoli G, Gelmetti C, Cucchi G et al. Long-term follow-up of dermatitis herpetiformis in children. Journal of the American Academy of Dermatology. 1986;15(1):24-30.
Ermacora, E. ; Prampolini, L. ; Tribbia, G. ; Pezzoli, G. ; Gelmetti, C. ; Cucchi, G. ; Tettamanti, A. ; Giunta, A. ; Gianotti, F. / Long-term follow-up of dermatitis herpetiformis in children. In: Journal of the American Academy of Dermatology. 1986 ; Vol. 15, No. 1. pp. 24-30.
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AU - Prampolini, L.

AU - Tribbia, G.

AU - Pezzoli, G.

AU - Gelmetti, C.

AU - Cucchi, G.

AU - Tettamanti, A.

AU - Giunta, A.

AU - Gianotti, F.

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