Long-term follow-up of endoscopic treatment of vesicoureteral reflux: Three-center experience

Boris Chertin, Alon Fridmans, Claudio Granata, Vincenzo Jasonni, Amicur Farkas, Prem Puri

Research output: Contribution to journalArticlepeer-review


Background: We reviewed our experience with subureteral polytetrafluoroethylene (Teflon) injection (STING) in the Treatm. of vesicoureteral reflux (VUR), with Spec. emphasis on long-term effectiveness/morbidity. Patients/Methods: From 1984 to 2001, 1916 patients, 488 male/1428 female (3037 refluxing ureters) with a mean age of 3.7 years (range, 3 months-15 years), were treated endoscopically with STING. Reflux was grade I in 154 (5.1%), II in 509 (16.8%), III in 1450 (47.7%), IV in 743 (24.5%),/V in 181 (6%) ureters. Prim. VUR, reflux in duplex systems,/reflux Secdry. to neuropathic bladder were present in 2778 (91.4 %), 205 (6.8%),/ 54 (1.8%) ureters, respectively. All patients were followed up for periods ranging from 1 to 18 years, with a median follow-up of 11 years. Results: Reflux resolved in 2032 (66.9%) ureters after one injection, in 776 (25.5%) after two, and in 111 (3.7%) after three injections. VUR improved to grade I after one or two injections in 81 (2.7%) ureters, which required no further treatment. Subureteral injection failed to correct reflux in 37 (1.2%), which then were treated with ureteral reimplantation. At follow-up, reflux had recurred in 41 (1.4%) ureters, and 23 of these had only grade I or II VUR. Conclusion: The results of this study confirm that endoscopic STING is a simple and effective outpatient procedure in the treatment of VUR. No long-term morbidity was observed in our patients with the use of polytetrafluoroethylene during 17 years of follow-up.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalPediatric Endosurgery and Innovative Techniques
Issue number1
Publication statusPublished - Mar 2003

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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