Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease

L. M A Romito, M. Scerrati, M. F. Contarino, A. R. Bentivoglio, P. Tonali, A. Albanese

Research output: Contribution to journalArticle

Abstract

Twenty-two patients with PD received bilateral implants for high frequency stimulation of the subthalamic nucleus. The patients were treated for more than 1 year (up to 36 months). At the last visit, the Unified Parkinson Disease Rating Scale (UPDRS) motor score without medication improved by 50.2% (p <0.001) and the UPDRS activities of daily living score improved by 68.4% (p <0.001). The most common long-lasting adverse events were hypophonia and dysarthria; transient events were increased sexuality and mania. The surgical procedure induced transient intraoperative psychosis in seven patients.

Original languageEnglish
Pages (from-to)1546-1550
Number of pages5
JournalNeurology
Volume58
Issue number10
Publication statusPublished - May 28 2002

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Subthalamic Nucleus
Parkinson Disease
Dysarthria
Sexuality
Activities of Daily Living
Bipolar Disorder
Psychotic Disorders

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Romito, L. M. A., Scerrati, M., Contarino, M. F., Bentivoglio, A. R., Tonali, P., & Albanese, A. (2002). Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease. Neurology, 58(10), 1546-1550.

Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease. / Romito, L. M A; Scerrati, M.; Contarino, M. F.; Bentivoglio, A. R.; Tonali, P.; Albanese, A.

In: Neurology, Vol. 58, No. 10, 28.05.2002, p. 1546-1550.

Research output: Contribution to journalArticle

Romito, LMA, Scerrati, M, Contarino, MF, Bentivoglio, AR, Tonali, P & Albanese, A 2002, 'Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease', Neurology, vol. 58, no. 10, pp. 1546-1550.
Romito LMA, Scerrati M, Contarino MF, Bentivoglio AR, Tonali P, Albanese A. Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease. Neurology. 2002 May 28;58(10):1546-1550.
Romito, L. M A ; Scerrati, M. ; Contarino, M. F. ; Bentivoglio, A. R. ; Tonali, P. ; Albanese, A. / Long-term follow up of subthalamic nucleus stimulation in Parkinson's disease. In: Neurology. 2002 ; Vol. 58, No. 10. pp. 1546-1550.
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