Long-term follow up with sparing surgery for testicular diseases: A safe choice in benign testicular lesions

Giorgio Bozzini, Stefano Picozzi, Dario Ratti, Stefano Casellato, Luca Carmignani

Research output: Contribution to journalArticlepeer-review


Objective: We performed a long-term evaluation of testicular conservative surgical treatment of benign conditions. Material and methods: Between January 2001 and January 2005, a single center perspective clinical study was performed at our Academic Department of Urology. Case files of all patients diagnosed with small testicular mass (less than 1.5. cm) and treated with conservative surgery were examined. Patients underwent physical examination, hormone and tumor marker assays, scrotal and abdominal ultrasound, chest X-ray and endocrinological examination. Should a benign disease or a selected malignant condition (Leydig cell tumor) be diagnosed during the frozen section analysis, testicular sparing surgery was performed. Each patient presenting a malignant condition underwent a strict oncological follow up according to the EAU Guidelines. Results: From January 2001 to January 2005, 80 patients with small testicular mass underwent conservative surgery. Patient mean age was 40.9 years. Mean follow up was 95.78 months. Patients presented either with a palpable testicular nodule (77.5%) or a nodule diagnosed by ultrasound (22.5%). Diagnosis after frozen section examination was Leydig cell tumor in 20 of 80 cases. Mean histological size of the nodule was 0.93. cm. Tumor markers were normal before and after surgery. Follow up was conducted for all malignant patients following EAU Guidelines. No local recurrence or metastasis were observed. 100% of patients are still alive. Conclusions: Testicular Sparing Surgery is feasible in all benign cases. Leydig cell tumors present a favorable long-term follow up when diagnosed early. Conservative surgery proved to be the safer choice.

Original languageEnglish
Pages (from-to)144-148
Number of pages5
JournalRevista Internacional de Andrologia
Issue number4
Publication statusPublished - Oct 2013


  • Frozen section examination
  • Testicular lesion
  • Testicular sparing surgery

ASJC Scopus subject areas

  • Urology
  • Reproductive Medicine


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