TY - JOUR
T1 - Long-term follow‐up outcomes after percutaneous us/ct‐guided radiofrequency ablation for ct1a‐b renal masses
T2 - Experience from single high‐volume referral center
AU - Mauri, Giovanni
AU - Mistretta, Francesco Alessandro
AU - Bonomo, Guido
AU - Camisassi, Nicola
AU - Conti, Andrea
AU - Vigna, Paolo Della
AU - Ferro, Matteo
AU - Luzzago, Stefano
AU - Maiettini, Daniele
AU - Musi, Gennaro
AU - Piacentini, Nicolò
AU - Varano, Gianluca Maria
AU - de Cobelli, Ottavio
AU - Orsi, Franco
N1 - Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/5
Y1 - 2020/5
N2 - Image‐guided thermal ablations are increasingly applied in the treatment of renal cancers, under the guidance of ultrasound (US) or computed tomography (CT). Sometimes, multiple ablations are needed. The aim of the present study was to evaluate the long‐term results in patients with renal mass treated with radiofrequency ablation (RFA) with both US and CT, with a focus on the multiple ablations rate. 149 patients (median age 67 years) underwent RFA from January 2008 to June 2015. Median tumor diameter was 25 mm (IQR 17–32 mm). Median follow‐up was 54 months (IQR 44–68). 27 (18.1%) patients received multiple successful ablations, due to incomplete ablation (10 patients), local tumor progression (8 patients), distant tumor progression (4 patients) or multiple tumor foci (5 patients), with a primary and secondary technical efficacy of 100%. Complications occurred in 13 (8.7%) patients (6 grade A, 5 grade C, 2 grade D). 24 patients died during follow‐up, all for causes unrelated to renal cancer. In conclusion, thermal ablations with the guidance of US and CT are safe and effective in the treatment of renal tumors in the long‐term period, with a low rate of patients requiring multiple treatments over the course of their disease.
AB - Image‐guided thermal ablations are increasingly applied in the treatment of renal cancers, under the guidance of ultrasound (US) or computed tomography (CT). Sometimes, multiple ablations are needed. The aim of the present study was to evaluate the long‐term results in patients with renal mass treated with radiofrequency ablation (RFA) with both US and CT, with a focus on the multiple ablations rate. 149 patients (median age 67 years) underwent RFA from January 2008 to June 2015. Median tumor diameter was 25 mm (IQR 17–32 mm). Median follow‐up was 54 months (IQR 44–68). 27 (18.1%) patients received multiple successful ablations, due to incomplete ablation (10 patients), local tumor progression (8 patients), distant tumor progression (4 patients) or multiple tumor foci (5 patients), with a primary and secondary technical efficacy of 100%. Complications occurred in 13 (8.7%) patients (6 grade A, 5 grade C, 2 grade D). 24 patients died during follow‐up, all for causes unrelated to renal cancer. In conclusion, thermal ablations with the guidance of US and CT are safe and effective in the treatment of renal tumors in the long‐term period, with a low rate of patients requiring multiple treatments over the course of their disease.
KW - Computed tomography
KW - Image‐guided thermal ablation
KW - Radiofrequency
KW - Renal cancer
KW - Survival
KW - Ultrasound
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U2 - 10.3390/cancers12051183
DO - 10.3390/cancers12051183
M3 - Article
AN - SCOPUS:85084613316
VL - 12
JO - Cancers
JF - Cancers
SN - 2072-6694
IS - 5
M1 - 1183
ER -