Long term growth hormone (GH)-releasing hormone and biosynthetic GH therapy in GH-deficient children: comparison of therapeutic effectiveness

M. Bozzola, I. Biscaldi, M. Cisternino, F. Severi, A. Balsamo, E. Cacciari, C. Pellini, G. Chiumello, G. L. Spadoni, B. Boscherini, S. Bernasconi, L. Benso, G. Cavagnini, E. Spolettini, F. Antoniazzi, L. Tatò

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-five GH-deficient children were treated with GHRH (1-44), once daily sc for 6–24 months. At the 6th month of therapy, 40% of our patients showed a catch-up growth (responded), while the remaining 60% did not (nonre-sponders). No differences in auxological and biological variables at inclusion were found between the two groups. However, integrated GH secretion elicited by iv GHRH at inclusion was significantly (p

Original languageEnglish
Pages (from-to)235-239
Number of pages5
JournalJournal of Endocrinological Investigation
Volume13
Issue number3
DOIs
Publication statusPublished - 1990

Keywords

  • GH therapy
  • GH-deficiency
  • GHRH therapy

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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