Abstract
Objective: To evaluate the neuroendocrine effect of naltrexone in the long-term treatment of polycystic ovary syndrome. Methods: The chronobiological secretory characteristics of the pituitary hormones FSH, LH, PRL, and cortisol were investigated over a period of 8 hours in a group of polycystic ovary syndrome patients before and after treatment with naltrexone (50 mg per os daily for 28 days). Results: No significant changes in integrated LH mean values and mean LH pulse frequency were found, whereas the mean LH pulse amplitude was significantly lower (p
Original language | English |
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Pages (from-to) | 64-68 |
Number of pages | 5 |
Journal | Italian Journal of Gynaecology and Obstetrics |
Volume | 5 |
Issue number | 2 |
Publication status | Published - 1993 |
ASJC Scopus subject areas
- Obstetrics and Gynaecology