TY - JOUR
T1 - Long-term natural history of highly myopic eyes with a dome-shaped macula with or without untreated serous retinal detachment
T2 - A 4-year follow-up study
AU - Viola, Francesco
AU - Leone, Gaia
AU - Garoli, Elena
AU - Mainetti, Claudia
AU - Galli, Davide
AU - Invernizzi, Alessandro
PY - 2021
Y1 - 2021
N2 - Purpose: To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD). Methods: This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6 months for 4 years. Eyes with choroidal neovascularisation were excluded. Results: Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69%) or round (31%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness. Conclusions: BCVA remained clinically stable over 4 years without treatment despite the fluctuations and persistence of the SRDs.
AB - Purpose: To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD). Methods: This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6 months for 4 years. Eyes with choroidal neovascularisation were excluded. Results: Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69%) or round (31%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness. Conclusions: BCVA remained clinically stable over 4 years without treatment despite the fluctuations and persistence of the SRDs.
KW - Imaging
KW - Macula
KW - Retina
KW - Vision
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U2 - 10.1136/bjophthalmol-2020-316629
DO - 10.1136/bjophthalmol-2020-316629
M3 - Article
C2 - 32892162
AN - SCOPUS:85091526431
VL - 105
SP - 1405
EP - 1409
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
SN - 0007-1161
IS - 10
ER -