Long-term natural history of highly myopic eyes with a dome-shaped macula with or without untreated serous retinal detachment: A 4-year follow-up study

Francesco Viola, Gaia Leone, Elena Garoli, Claudia Mainetti, Davide Galli, Alessandro Invernizzi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD). Methods: This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6 months for 4 years. Eyes with choroidal neovascularisation were excluded. Results: Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69%) or round (31%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness. Conclusions: BCVA remained clinically stable over 4 years without treatment despite the fluctuations and persistence of the SRDs.

Original languageEnglish
Article numberbjophthalmol-2020-316629
JournalBritish Journal of Ophthalmology
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • Imaging
  • Macula
  • Retina
  • Vision

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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