TY - JOUR
T1 - Long Term Non-invasive Ventilation in Children With Central Hypoventilation
AU - Paglietti, Maria Giovanna
AU - Esposito, Irene
AU - Goia, Manuela
AU - Rizza, Elvira
AU - Cutrera, Renato
AU - Bignamini, Elisabetta
N1 - Publisher Copyright:
© Copyright © 2020 Paglietti, Esposito, Goia, Rizza, Cutrera and Bignamini.
PY - 2020/6/19
Y1 - 2020/6/19
N2 - Central hypoventilation (CH) is a quite rare disorder caused by some congenital or acquired conditions. It is featured by increased arterial concentration of serum carbon dioxide related to an impairment of respiratory drive. Patients affected by CH need to be treated by mechanical ventilation in order to achieve appropriate ventilation and oxygenation both in sleep and wakefulness. In fact, in severe form of Congenital Central Hypoventilation Syndrome (CCHS) hypercarbia can be present even during the day. Positive pressure ventilation via tracheostomy is the first therapeutic option in this clinical condition, especially in congenital forms. Non-Invasive ventilation is a an option that must be reserved for more stable clinical situations and that requires careful monitoring over time.
AB - Central hypoventilation (CH) is a quite rare disorder caused by some congenital or acquired conditions. It is featured by increased arterial concentration of serum carbon dioxide related to an impairment of respiratory drive. Patients affected by CH need to be treated by mechanical ventilation in order to achieve appropriate ventilation and oxygenation both in sleep and wakefulness. In fact, in severe form of Congenital Central Hypoventilation Syndrome (CCHS) hypercarbia can be present even during the day. Positive pressure ventilation via tracheostomy is the first therapeutic option in this clinical condition, especially in congenital forms. Non-Invasive ventilation is a an option that must be reserved for more stable clinical situations and that requires careful monitoring over time.
KW - arterial concentration of serum carbon dioxide
KW - central apnea
KW - central hypoventilation
KW - children
KW - non-invasive ventilation
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U2 - 10.3389/fped.2020.00288
DO - 10.3389/fped.2020.00288
M3 - Review article
AN - SCOPUS:85087290412
VL - 8
JO - Frontiers in Pediatrics
JF - Frontiers in Pediatrics
SN - 2296-2360
M1 - 288
ER -