Long-term prognosis of patients with cardiac syndrome X

Priscilla Lamendola, Gaetano A. Lanza, Antonella Spinelli, Gregory A. Sgueglia, Antonio Di Monaco, Lucy Barone, Alfonso Sestito, Filippo Crea

Research output: Contribution to journalArticle

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Abstract

Background: Previous follow-up studies of patients with cardiac syndrome X (CSX) reported good prognosis. However, some recent reports challenged this finding by showing appreciable mortality rates in patients with angina and normal coronary arteries admitted for acute coronary syndromes. Methods: We performed clinical follow-up of 155 patients (mean age 58.9 ± 10 years, 40 men) with typical CSX. The occurrence of major cardiac events (cardiac death, acute myocardial infarction), readmission for chest pain, revascularization procedures, angina status, and non cardiac events during follow-up were collected for each patient. Results: At a mean follow-up time of 137 ± 78 months (range 24-372) from the onset of symptoms, 4 patients died, 3 for cancers and 1 for acute pancreatitis. No patient died from cardiovascular causes or had any major cardiovascular event. Hospital readmission for recurrent chest pain was reported by 89 patients (58%), and 33 (22%) underwent at least one more coronary angiography. During follow-up, chest pain had remained unchanged in 33% of patients and had worsened in 14% of patients. Conclusion: Our data show that patients with CSX have excellent long-term clinical prognosis. A significant number of patients, however, shows persistence or worsening of symptoms, as well as further recurrence to medical evaluation.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalInternational Journal of Cardiology
Volume140
Issue number2
DOIs
Publication statusPublished - Apr 15 2010

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Microvascular Angina
Chest Pain
Patient Readmission
Acute Coronary Syndrome
Coronary Angiography
Pancreatitis

Keywords

  • Cardiac syndrome X
  • Prognosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Lamendola, P., Lanza, G. A., Spinelli, A., Sgueglia, G. A., Di Monaco, A., Barone, L., ... Crea, F. (2010). Long-term prognosis of patients with cardiac syndrome X. International Journal of Cardiology, 140(2), 197-199. https://doi.org/10.1016/j.ijcard.2008.11.026

Long-term prognosis of patients with cardiac syndrome X. / Lamendola, Priscilla; Lanza, Gaetano A.; Spinelli, Antonella; Sgueglia, Gregory A.; Di Monaco, Antonio; Barone, Lucy; Sestito, Alfonso; Crea, Filippo.

In: International Journal of Cardiology, Vol. 140, No. 2, 15.04.2010, p. 197-199.

Research output: Contribution to journalArticle

Lamendola, P, Lanza, GA, Spinelli, A, Sgueglia, GA, Di Monaco, A, Barone, L, Sestito, A & Crea, F 2010, 'Long-term prognosis of patients with cardiac syndrome X', International Journal of Cardiology, vol. 140, no. 2, pp. 197-199. https://doi.org/10.1016/j.ijcard.2008.11.026
Lamendola P, Lanza GA, Spinelli A, Sgueglia GA, Di Monaco A, Barone L et al. Long-term prognosis of patients with cardiac syndrome X. International Journal of Cardiology. 2010 Apr 15;140(2):197-199. https://doi.org/10.1016/j.ijcard.2008.11.026
Lamendola, Priscilla ; Lanza, Gaetano A. ; Spinelli, Antonella ; Sgueglia, Gregory A. ; Di Monaco, Antonio ; Barone, Lucy ; Sestito, Alfonso ; Crea, Filippo. / Long-term prognosis of patients with cardiac syndrome X. In: International Journal of Cardiology. 2010 ; Vol. 140, No. 2. pp. 197-199.
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