TY - JOUR
T1 - Long-term prognosis of patients with pediatric pheochromocytoma
AU - Bausch, Birke
AU - Wellner, Ulrich
AU - Bausch, Dirk
AU - Schiavi, Francesca
AU - Barontini, Marta
AU - Sanso, Gabriela
AU - Walz, Martin K.
AU - Peczkowska, Mariola
AU - Weryha, Georges
AU - Dall'Igna, Patrizia
AU - Cecchetto, Giovanni
AU - Bisogno, Gianni
AU - Moeller, Lars C.
AU - Bockenhauer, Detlef
AU - Patocs, Attila
AU - Rácz, Karoly
AU - Zabolotnyi, Dmitry
AU - Yaremchuk, Svetlana
AU - Dzivite-Krisane, Iveta
AU - Castinetti, Frederic
AU - Taieb, David
AU - Malinoc, Angelica
AU - Von Dobschuetz, Ernst
AU - Roessler, Jochen
AU - Schmid, Kurt W.
AU - Opocher, Giuseppe
AU - Eng, Charis
AU - Neumann, Hartmut P H
PY - 2014/2
Y1 - 2014/2
N2 - A third of patients with paraganglial tumors, pheochromocytoma, and paraganglioma, carry germline mutations in one of the susceptibility genes, RET, VHL, NF1, SDHAF2, SDHA, SDHB, SDHC, SDHD, TMEM127, and MAX. Despite increasing importance, data for long-term prognosis are scarce in pediatric presentations. The European-American-Pheochromocytoma-Paraganglioma-Registry, with a total of 2001 patients with confirmed paraganglial tumors, was the platform for this study. Molecular genetic and phenotypic classification and assessment of gene-specific long-term outcome with second and/or malignant paraganglial tumors and life expectancy were performed in patients diagnosed at
AB - A third of patients with paraganglial tumors, pheochromocytoma, and paraganglioma, carry germline mutations in one of the susceptibility genes, RET, VHL, NF1, SDHAF2, SDHA, SDHB, SDHC, SDHD, TMEM127, and MAX. Despite increasing importance, data for long-term prognosis are scarce in pediatric presentations. The European-American-Pheochromocytoma-Paraganglioma-Registry, with a total of 2001 patients with confirmed paraganglial tumors, was the platform for this study. Molecular genetic and phenotypic classification and assessment of gene-specific long-term outcome with second and/or malignant paraganglial tumors and life expectancy were performed in patients diagnosed at
KW - Germline mutations
KW - Long-term follow-up
KW - Pheochromocytoma
KW - Relapse
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U2 - 10.1530/ERC-13-0415
DO - 10.1530/ERC-13-0415
M3 - Article
C2 - 24169644
AN - SCOPUS:84893617173
VL - 21
SP - 17
EP - 25
JO - Endocrine-Related Cancer
JF - Endocrine-Related Cancer
SN - 1351-0088
IS - 1
ER -