Long-term prognosis of young breast cancer patients (

Gwen Mhe Dackus, Natalie D. Ter Hoeve, Mark Opdam, Willem Vreuls, Zsuzsanna Varga, Esther Koop, Stefan M. Willems, Carolien Hm Van Deurzen, Emilie J. Groen, Alicia Cordoba, Jos Bart, Antien L. Mooyaart, Jan G. van den Tweel, Vicky Zolota, Jelle Wesseling, Anna Sapino, Ewa Chmielik, Ales Ryska, Frederic Amant, Annegien BroeksRon Kerkhoven, Nikolas Stathonikos, Mitko Veta, Adri Voogd, Katarzyna Jozwiak, Michael Hauptmann, Marlous Hoogstraat, Marjanka K. Schmidt, Gabe Sonke, Elsken van der Wall, Sabine Siesling, Paul J. van Diest, Sabine C. Linn

Research output: Contribution to journalArticle

Abstract

INTRODUCTION: Currently used tools for breast cancer prognostication and prediction may not adequately reflect a young patient's prognosis or likely treatment benefit because they were not adequately validated in young patients. Since breast cancers diagnosed at a young age are considered prognostically unfavourable, many treatment guidelines recommend adjuvant systemic treatment for all young patients. Patients cured by locoregional treatment alone are, therefore, overtreated. Lack of prognosticators for young breast cancer patients represents an unmet medical need and has led to the initiation of the PAtients with bReAst cancer DIaGnosed preMenopausally (PARADIGM) initiative. Our aim is to reduce overtreatment of women diagnosed with breast cancer aged
Original languageEnglish
Pages (from-to)e017842
JournalBMJ Open
Volume7
Publication statusPublished - Nov 1 2017

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Breast Neoplasms
Therapeutics
Guidelines

Keywords

  • breast tumours, epidemiology, histopathology

Cite this

Dackus, G. M., Ter Hoeve, N. D., Opdam, M., Vreuls, W., Varga, Z., Koop, E., ... Linn, S. C. (2017). Long-term prognosis of young breast cancer patients (. BMJ Open, 7, e017842.

Long-term prognosis of young breast cancer patients (. / Dackus, Gwen Mhe; Ter Hoeve, Natalie D.; Opdam, Mark; Vreuls, Willem; Varga, Zsuzsanna; Koop, Esther; Willems, Stefan M.; Van Deurzen, Carolien Hm; Groen, Emilie J.; Cordoba, Alicia; Bart, Jos; Mooyaart, Antien L.; van den Tweel, Jan G.; Zolota, Vicky; Wesseling, Jelle; Sapino, Anna; Chmielik, Ewa; Ryska, Ales; Amant, Frederic; Broeks, Annegien; Kerkhoven, Ron; Stathonikos, Nikolas; Veta, Mitko; Voogd, Adri; Jozwiak, Katarzyna; Hauptmann, Michael; Hoogstraat, Marlous; Schmidt, Marjanka K.; Sonke, Gabe; van der Wall, Elsken; Siesling, Sabine; van Diest, Paul J.; Linn, Sabine C.

In: BMJ Open, Vol. 7, 01.11.2017, p. e017842.

Research output: Contribution to journalArticle

Dackus, GM, Ter Hoeve, ND, Opdam, M, Vreuls, W, Varga, Z, Koop, E, Willems, SM, Van Deurzen, CH, Groen, EJ, Cordoba, A, Bart, J, Mooyaart, AL, van den Tweel, JG, Zolota, V, Wesseling, J, Sapino, A, Chmielik, E, Ryska, A, Amant, F, Broeks, A, Kerkhoven, R, Stathonikos, N, Veta, M, Voogd, A, Jozwiak, K, Hauptmann, M, Hoogstraat, M, Schmidt, MK, Sonke, G, van der Wall, E, Siesling, S, van Diest, PJ & Linn, SC 2017, 'Long-term prognosis of young breast cancer patients (', BMJ Open, vol. 7, pp. e017842.
Dackus GM, Ter Hoeve ND, Opdam M, Vreuls W, Varga Z, Koop E et al. Long-term prognosis of young breast cancer patients (. BMJ Open. 2017 Nov 1;7:e017842.
Dackus, Gwen Mhe ; Ter Hoeve, Natalie D. ; Opdam, Mark ; Vreuls, Willem ; Varga, Zsuzsanna ; Koop, Esther ; Willems, Stefan M. ; Van Deurzen, Carolien Hm ; Groen, Emilie J. ; Cordoba, Alicia ; Bart, Jos ; Mooyaart, Antien L. ; van den Tweel, Jan G. ; Zolota, Vicky ; Wesseling, Jelle ; Sapino, Anna ; Chmielik, Ewa ; Ryska, Ales ; Amant, Frederic ; Broeks, Annegien ; Kerkhoven, Ron ; Stathonikos, Nikolas ; Veta, Mitko ; Voogd, Adri ; Jozwiak, Katarzyna ; Hauptmann, Michael ; Hoogstraat, Marlous ; Schmidt, Marjanka K. ; Sonke, Gabe ; van der Wall, Elsken ; Siesling, Sabine ; van Diest, Paul J. ; Linn, Sabine C. / Long-term prognosis of young breast cancer patients (. In: BMJ Open. 2017 ; Vol. 7. pp. e017842.
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