Long-term prognostic utility of computed tomography coronary angiography in older populations

Sonali R. Gnanenthiran, Christopher Naoum, Jonathon A. Leipsic, Stephan Achenbach, Mouaz H. Al-Mallah, Daniele Andreini, Jeroen J. Bax, Daniel S. Berman, Matthew J. Budoff, Filippo Cademartiri, Tracy Q. Callister, Hyuk Jae Chang, Kavitha Chinnaiyan, Benjamin J.W. Chow, Ricardo C. Cury, Augustin Delago, Gudrun Feuchtner, Martin Hadamitzky, Joerg Hausleiter, Philipp A. KaufmanYong Jin Kim, Erica Maffei, Hugo Marques, Pedro De Araújo Goncalves, Gianluca Pontone, Gilbert L. Raff, Ronen Rubinshtein, Leslee J. Shaw, Todd C. Villines, Heidi Gransar, Yao Lu, Erica C. Jones, Jessica M. Penã, Fay Y. Lin, Leonard Kritharides, James K. Min

Research output: Contribution to journalArticlepeer-review


Aims: The long-term prognostic value of coronary computed tomography angiography (CCTA)-identified coronary artery disease (CAD) has not been evaluated in elderly patients (≥70 years). We compared the ability of coronary CCTA to predict 5-year mortality in older vs. younger populations. Methods and results: From the prospective CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) registry, we analysed CCTA results according to age 50%); (ii) segment involvement score (SIS): Number of segments with plaque. Cox-proportional hazard models assessed the relationship between CCTA findings and time to mortality. At a mean 5.6 ± 1.1 year follow-up, CCTA-identified CAD predicted increased mortality compared with patients with a normal CCTA in both
Original languageEnglish
Pages (from-to)1279-1286
Number of pages8
JournalEuropean Heart Journal Cardiovascular Imaging
Issue number11
Publication statusPublished - Nov 1 2019


  • age
  • coronary computed tomography angiography
  • major adverse cardiovascular events
  • mortality
  • older populations


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