Abstract
The hypothesis has been advanced that cardiovascular prognosis is related not only to 24-hour mean blood pressure but also to blood pressure variability. Data, however, are inconsistent, and no long-term prognostic study is available. In 2012 individuals randomly selected from the population of Monza (Milan), 24-hour ambulatory blood pressure (Spacelabs 90207) was measured via readings spaced by 20 minutes. Systolic and diastolic blood pressure variability was obtained by calculating the following: (1) the SD of 24-hour, day, and night mean values; (2) the day-night blood pressure difference; and (3) the residual or erratic blood pressure variability (Fourier spectral analysis). Fatal cardiovascular and noncardiovascular events were registered for 148 months. When adjusted for age, sex, 24-hour mean blood pressure, and other risk factors, there was no relationship between the risk of death and 24-hour, day, and night blood pressure SDs. In contrast, the adjusted risk of cardiovascular death was inversely related to day-night diastolic BP difference (β coefficient=-0.040; P
| Original language | English |
|---|---|
| Pages (from-to) | 1265-1270 |
| Number of pages | 6 |
| Journal | Hypertension |
| Volume | 49 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2007 |
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Keywords
- Blood pressure monitoring
- Blood pressure variability
- Morbidity
- Mortality
- Population science
- Risk factors
ASJC Scopus subject areas
- Internal Medicine
Cite this
Long-term prognostic value of blood pressure variability in the general population : Results of the Pressioni Arteriose Monitorate e Lassociazioni Study. / Mancia, Giuseppe; Bombelli, Michele; Facchetti, Rita; Madotto, Fabiana; Corrao, Giovanni; Trevano, Fosca Quarti; Grassi, Guido; Sega, Roberto.
In: Hypertension, Vol. 49, No. 6, 06.2007, p. 1265-1270.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term prognostic value of blood pressure variability in the general population
T2 - Results of the Pressioni Arteriose Monitorate e Lassociazioni Study
AU - Mancia, Giuseppe
AU - Bombelli, Michele
AU - Facchetti, Rita
AU - Madotto, Fabiana
AU - Corrao, Giovanni
AU - Trevano, Fosca Quarti
AU - Grassi, Guido
AU - Sega, Roberto
PY - 2007/6
Y1 - 2007/6
N2 - The hypothesis has been advanced that cardiovascular prognosis is related not only to 24-hour mean blood pressure but also to blood pressure variability. Data, however, are inconsistent, and no long-term prognostic study is available. In 2012 individuals randomly selected from the population of Monza (Milan), 24-hour ambulatory blood pressure (Spacelabs 90207) was measured via readings spaced by 20 minutes. Systolic and diastolic blood pressure variability was obtained by calculating the following: (1) the SD of 24-hour, day, and night mean values; (2) the day-night blood pressure difference; and (3) the residual or erratic blood pressure variability (Fourier spectral analysis). Fatal cardiovascular and noncardiovascular events were registered for 148 months. When adjusted for age, sex, 24-hour mean blood pressure, and other risk factors, there was no relationship between the risk of death and 24-hour, day, and night blood pressure SDs. In contrast, the adjusted risk of cardiovascular death was inversely related to day-night diastolic BP difference (β coefficient=-0.040; P
AB - The hypothesis has been advanced that cardiovascular prognosis is related not only to 24-hour mean blood pressure but also to blood pressure variability. Data, however, are inconsistent, and no long-term prognostic study is available. In 2012 individuals randomly selected from the population of Monza (Milan), 24-hour ambulatory blood pressure (Spacelabs 90207) was measured via readings spaced by 20 minutes. Systolic and diastolic blood pressure variability was obtained by calculating the following: (1) the SD of 24-hour, day, and night mean values; (2) the day-night blood pressure difference; and (3) the residual or erratic blood pressure variability (Fourier spectral analysis). Fatal cardiovascular and noncardiovascular events were registered for 148 months. When adjusted for age, sex, 24-hour mean blood pressure, and other risk factors, there was no relationship between the risk of death and 24-hour, day, and night blood pressure SDs. In contrast, the adjusted risk of cardiovascular death was inversely related to day-night diastolic BP difference (β coefficient=-0.040; P
KW - Blood pressure monitoring
KW - Blood pressure variability
KW - Morbidity
KW - Mortality
KW - Population science
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=34249289026&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249289026&partnerID=8YFLogxK
U2 - 10.1161/HYPERTENSIONAHA.107.088708
DO - 10.1161/HYPERTENSIONAHA.107.088708
M3 - Article
C2 - 17452502
AN - SCOPUS:34249289026
VL - 49
SP - 1265
EP - 1270
JO - Hypertension
JF - Hypertension
SN - 0194-911X
IS - 6
ER -