Long-term quality of life after esophagectomy with gastric pull-up

Silvia Mantoan, Francesco Cavallin, Eleonora Pinto, Luca M Saadeh, Rita Alfieri, Matteo Cagol, Maria C Bellissimo, Carlo Castoro, Marco Scarpa

Research output: Contribution to journalArticle

Abstract

BACKGROUND AND OBJECTIVES: Data on long-term health-related quality of life (HRQL) after esophagectomy for cancer show contradictory results. The aim was to analyze long-term HRQL at 3 or more years after esophagectomy.

METHODS: Survivors were identified among patients who had undergone esophagectomy during 2007-2013 using the local clinic database. Quality of life was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and OG25 questionnaires. Specific aspects were selected a priori and compared with published scores from European healthy subjects (mean difference, MD).

RESULTS: Sixty-five long-term survivors (median follow-up 4 years) were identified. All functional scales and most symptom scales were clinically similar between EC long-term survivors and European healthy subjects. Survivors reported more problems concerning eating (MD 13.1, 95% C.I. 10.6-15.6) and reflux (MD 19.7, 95% C.I. 15.9-23.5). HQRL variation from discharge to long term was available in 27 participants who reported improvements in role functioning (MD 40.1, 95%C.I. 24.3-56.0) and dysphagia (MD -41.9, 95% C.I. -51.7 to 32.0).

CONCLUSIONS: Long-term HRQL after esophagectomy is similar between EC survivors and European healthy subjects, despite persisting reflux and eating problems. Further research may focus on improvements of postoperative alimentary habits.

Original languageEnglish
Pages (from-to)970-976
Number of pages7
JournalJournal of Surgical Oncology
Volume117
Issue number5
DOIs
Publication statusPublished - Apr 2018

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Esophagectomy
Survivors
Stomach
Quality of Life
Healthy Volunteers
Eating
Deglutition Disorders
Research
Habits
Neoplasms
Organizations
Databases

Keywords

  • Adenocarcinoma/surgery
  • Aged
  • Carcinoma, Squamous Cell/surgery
  • Esophageal Neoplasms/surgery
  • Esophagectomy/adverse effects
  • Female
  • Follow-Up Studies
  • Gastroesophageal Reflux/etiology
  • Health Status
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications
  • Prognosis
  • Quality of Life
  • Surveys and Questionnaires
  • Survivors

Cite this

Long-term quality of life after esophagectomy with gastric pull-up. / Mantoan, Silvia; Cavallin, Francesco; Pinto, Eleonora; Saadeh, Luca M; Alfieri, Rita; Cagol, Matteo; Bellissimo, Maria C; Castoro, Carlo; Scarpa, Marco.

In: Journal of Surgical Oncology, Vol. 117, No. 5, 04.2018, p. 970-976.

Research output: Contribution to journalArticle

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abstract = "BACKGROUND AND OBJECTIVES: Data on long-term health-related quality of life (HRQL) after esophagectomy for cancer show contradictory results. The aim was to analyze long-term HRQL at 3 or more years after esophagectomy.METHODS: Survivors were identified among patients who had undergone esophagectomy during 2007-2013 using the local clinic database. Quality of life was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and OG25 questionnaires. Specific aspects were selected a priori and compared with published scores from European healthy subjects (mean difference, MD).RESULTS: Sixty-five long-term survivors (median follow-up 4 years) were identified. All functional scales and most symptom scales were clinically similar between EC long-term survivors and European healthy subjects. Survivors reported more problems concerning eating (MD 13.1, 95{\%} C.I. 10.6-15.6) and reflux (MD 19.7, 95{\%} C.I. 15.9-23.5). HQRL variation from discharge to long term was available in 27 participants who reported improvements in role functioning (MD 40.1, 95{\%}C.I. 24.3-56.0) and dysphagia (MD -41.9, 95{\%} C.I. -51.7 to 32.0).CONCLUSIONS: Long-term HRQL after esophagectomy is similar between EC survivors and European healthy subjects, despite persisting reflux and eating problems. Further research may focus on improvements of postoperative alimentary habits.",
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author = "Silvia Mantoan and Francesco Cavallin and Eleonora Pinto and Saadeh, {Luca M} and Rita Alfieri and Matteo Cagol and Bellissimo, {Maria C} and Carlo Castoro and Marco Scarpa",
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T1 - Long-term quality of life after esophagectomy with gastric pull-up

AU - Mantoan, Silvia

AU - Cavallin, Francesco

AU - Pinto, Eleonora

AU - Saadeh, Luca M

AU - Alfieri, Rita

AU - Cagol, Matteo

AU - Bellissimo, Maria C

AU - Castoro, Carlo

AU - Scarpa, Marco

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N2 - BACKGROUND AND OBJECTIVES: Data on long-term health-related quality of life (HRQL) after esophagectomy for cancer show contradictory results. The aim was to analyze long-term HRQL at 3 or more years after esophagectomy.METHODS: Survivors were identified among patients who had undergone esophagectomy during 2007-2013 using the local clinic database. Quality of life was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and OG25 questionnaires. Specific aspects were selected a priori and compared with published scores from European healthy subjects (mean difference, MD).RESULTS: Sixty-five long-term survivors (median follow-up 4 years) were identified. All functional scales and most symptom scales were clinically similar between EC long-term survivors and European healthy subjects. Survivors reported more problems concerning eating (MD 13.1, 95% C.I. 10.6-15.6) and reflux (MD 19.7, 95% C.I. 15.9-23.5). HQRL variation from discharge to long term was available in 27 participants who reported improvements in role functioning (MD 40.1, 95%C.I. 24.3-56.0) and dysphagia (MD -41.9, 95% C.I. -51.7 to 32.0).CONCLUSIONS: Long-term HRQL after esophagectomy is similar between EC survivors and European healthy subjects, despite persisting reflux and eating problems. Further research may focus on improvements of postoperative alimentary habits.

AB - BACKGROUND AND OBJECTIVES: Data on long-term health-related quality of life (HRQL) after esophagectomy for cancer show contradictory results. The aim was to analyze long-term HRQL at 3 or more years after esophagectomy.METHODS: Survivors were identified among patients who had undergone esophagectomy during 2007-2013 using the local clinic database. Quality of life was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and OG25 questionnaires. Specific aspects were selected a priori and compared with published scores from European healthy subjects (mean difference, MD).RESULTS: Sixty-five long-term survivors (median follow-up 4 years) were identified. All functional scales and most symptom scales were clinically similar between EC long-term survivors and European healthy subjects. Survivors reported more problems concerning eating (MD 13.1, 95% C.I. 10.6-15.6) and reflux (MD 19.7, 95% C.I. 15.9-23.5). HQRL variation from discharge to long term was available in 27 participants who reported improvements in role functioning (MD 40.1, 95%C.I. 24.3-56.0) and dysphagia (MD -41.9, 95% C.I. -51.7 to 32.0).CONCLUSIONS: Long-term HRQL after esophagectomy is similar between EC survivors and European healthy subjects, despite persisting reflux and eating problems. Further research may focus on improvements of postoperative alimentary habits.

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KW - Follow-Up Studies

KW - Gastroesophageal Reflux/etiology

KW - Health Status

KW - Humans

KW - Male

KW - Middle Aged

KW - Postoperative Complications

KW - Prognosis

KW - Quality of Life

KW - Surveys and Questionnaires

KW - Survivors

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JO - Journal of Surgical Oncology

JF - Journal of Surgical Oncology

SN - 0022-4790

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