Long-term results of combined ESWL and ERCP treatment of chronic calcific pancreatitis

Taija Korpela, Marianne Udd, Andrea Tenca, Outi Lindström, Jorma Halttunen, Sanna Myrskysalo, Arto Mikkola, Leena Kylänpää

Research output: Contribution to journalArticle

Abstract

Objective Extracorporeal shock wave lithotripsy (ESWL) combined with endotherapy (ET) is the standard treatment for pancreatic duct stones (PDS) in chronic pancreatitis (CP). Our aim was to report the short- and long-term results of ESWL and ET. Material and methods Consecutively treated 83 patients with symptomatic PDS using ESWL and ET. Success was defined (i) technically: PDS fragmentation and clearance obtained and (ii) clinically: improvement/resolution of pain. To get information on quality of life, we conducted a phone survey whereby we contacted 64 (89%) patients. The long-term results are presented in those patients with ≥2 years follow-up. Results Treated PDS with median size of 10 (5–25) mm were located in the head, body, or the tail of the pancreas in 78, 4, and 1 patients, respectively. The primary results were that technical success was achieved in 69 patients (83%) and clinical success in 66 patients (80%). Fourteen patients had technical failure, but eight of them became free of pain. Thus, clinical success can be considered to have been achieved in 74 of 83 patients (89%). In patients with persistent pseudocyst (PC) at the time of ESWL (n = 19), the PC disappeared in a year in 14 patients (74%). The long-term results were obtained from 61 (73%) ESWL- and ET-treated patients. The median follow-up for them was 53 months (range: 24–124) and 57 patients (93%) became pain-free or had less pain. Conclusions For patients with CP and PDS ESWL combined with ET is an effective and safe treatment giving favorable long-term results.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalScandinavian Journal of Gastroenterology
DOIs
Publication statusAccepted/In press - Feb 22 2016

Keywords

  • Endotherapy
  • lithotripsy
  • pancreatic calculi
  • pancreatic duct stones
  • shockwave

ASJC Scopus subject areas

  • Gastroenterology

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    Korpela, T., Udd, M., Tenca, A., Lindström, O., Halttunen, J., Myrskysalo, S., Mikkola, A., & Kylänpää, L. (Accepted/In press). Long-term results of combined ESWL and ERCP treatment of chronic calcific pancreatitis. Scandinavian Journal of Gastroenterology, 1-6. https://doi.org/10.3109/00365521.2016.1150502