Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience

Fiorina Giona; Maria C. Putti; Concetta Micalizzi; Giuseppe Menna; Maria L. Moleti; Nicola Santoro; Grazia Iaria; Saverio Ladogana; Roberta Burnelli; Caterina Consarino; Stefania Varotto; Francesca Tucci; Chiara Messina; Mauro Nanni; Daniela Diverio; Andrea Biondi; Andrea Pession; Franco Locatelli; Alfonso Piciocchi; Enrico Gottardi; Giuseppe Saglio; Robin Foà

doi:10.1111/bjh.13453

Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience

Fiorina Giona, Maria C. Putti, Concetta Micalizzi, Giuseppe Menna, Maria L. Moleti, Nicola Santoro, Grazia Iaria, Saverio Ladogana, Roberta Burnelli, Caterina Consarino, Stefania Varotto, Francesca Tucci, Chiara Messina, Mauro Nanni, Daniela Diverio, Andrea Biondi, Andrea Pession, Franco Locatelli, Alfonso Piciocchi, Enrico GottardiGiuseppe Saglio, Robin Foà

Research output: Contribution to journal › Article › peer-review

Abstract

Imatinib mesylate (IM) is used for the management of childhood chronic myeloid leukaemia (CML). The most effective dosage of IM and its long-term efficacy in children are not well defined. The purpose of this multicentre study is to report on the long-term results of high-dose IM (340 mg/m2 /d) in CML patients in chronic phase (CP-CML) aged

Original language	English
Pages (from-to)	398-407
Number of pages	10
Journal	British Journal of Haematology
Volume	170
Issue number	3
DOIs	https://doi.org/10.1111/bjh.13453
Publication status	Published - Aug 1 2015

Keywords

BCR-ABL1
childhood
chronic myeloid leukaemia
imatinib
tyrosine kinase inhibitors

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1111/bjh.13453

Cite this

Giona, F., Putti, M. C., Micalizzi, C., Menna, G., Moleti, M. L., Santoro, N., Iaria, G., Ladogana, S., Burnelli, R., Consarino, C., Varotto, S., Tucci, F., Messina, C., Nanni, M., Diverio, D., Biondi, A., Pession, A., Locatelli, F., Piciocchi, A., ... Foà, R. (2015). Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience. British Journal of Haematology, 170(3), 398-407. https://doi.org/10.1111/bjh.13453

Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase : the Italian experience. / Giona, Fiorina; Putti, Maria C.; Micalizzi, Concetta; Menna, Giuseppe; Moleti, Maria L.; Santoro, Nicola; Iaria, Grazia; Ladogana, Saverio; Burnelli, Roberta; Consarino, Caterina; Varotto, Stefania; Tucci, Francesca; Messina, Chiara; Nanni, Mauro; Diverio, Daniela; Biondi, Andrea; Pession, Andrea; Locatelli, Franco; Piciocchi, Alfonso; Gottardi, Enrico; Saglio, Giuseppe; Foà, Robin.

In: British Journal of Haematology, Vol. 170, No. 3, 01.08.2015, p. 398-407.

Research output: Contribution to journal › Article › peer-review

Giona, F, Putti, MC, Micalizzi, C, Menna, G, Moleti, ML, Santoro, N, Iaria, G, Ladogana, S, Burnelli, R, Consarino, C, Varotto, S, Tucci, F, Messina, C, Nanni, M, Diverio, D, Biondi, A, Pession, A, Locatelli, F, Piciocchi, A, Gottardi, E, Saglio, G & Foà, R 2015, 'Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience', British Journal of Haematology, vol. 170, no. 3, pp. 398-407. https://doi.org/10.1111/bjh.13453

Giona, Fiorina ; Putti, Maria C. ; Micalizzi, Concetta ; Menna, Giuseppe ; Moleti, Maria L. ; Santoro, Nicola ; Iaria, Grazia ; Ladogana, Saverio ; Burnelli, Roberta ; Consarino, Caterina ; Varotto, Stefania ; Tucci, Francesca ; Messina, Chiara ; Nanni, Mauro ; Diverio, Daniela ; Biondi, Andrea ; Pession, Andrea ; Locatelli, Franco ; Piciocchi, Alfonso ; Gottardi, Enrico ; Saglio, Giuseppe ; Foà, Robin. / Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase : the Italian experience. In: British Journal of Haematology. 2015 ; Vol. 170, No. 3. pp. 398-407.

@article{8cbf249f4b3b46b28ec06519eeb5a4bd,

title = "Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience",

abstract = "Imatinib mesylate (IM) is used for the management of childhood chronic myeloid leukaemia (CML). The most effective dosage of IM and its long-term efficacy in children are not well defined. The purpose of this multicentre study is to report on the long-term results of high-dose IM (340 mg/m2 /d) in CML patients in chronic phase (CP-CML) aged ",

keywords = "BCR-ABL1, childhood, chronic myeloid leukaemia, imatinib, tyrosine kinase inhibitors",

author = "Fiorina Giona and Putti, {Maria C.} and Concetta Micalizzi and Giuseppe Menna and Moleti, {Maria L.} and Nicola Santoro and Grazia Iaria and Saverio Ladogana and Roberta Burnelli and Caterina Consarino and Stefania Varotto and Francesca Tucci and Chiara Messina and Mauro Nanni and Daniela Diverio and Andrea Biondi and Andrea Pession and Franco Locatelli and Alfonso Piciocchi and Enrico Gottardi and Giuseppe Saglio and Robin Fo{\`a}",

year = "2015",

month = aug,

day = "1",

doi = "10.1111/bjh.13453",

language = "English",

volume = "170",

pages = "398--407",

journal = "British Journal of Haematology",

issn = "0007-1048",

publisher = "John Wiley & Sons, Ltd (10.1111)",

number = "3",

}

TY - JOUR

T1 - Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase

T2 - the Italian experience

AU - Giona, Fiorina

AU - Putti, Maria C.

AU - Micalizzi, Concetta

AU - Menna, Giuseppe

AU - Moleti, Maria L.

AU - Santoro, Nicola

AU - Iaria, Grazia

AU - Ladogana, Saverio

AU - Burnelli, Roberta

AU - Consarino, Caterina

AU - Varotto, Stefania

AU - Tucci, Francesca

AU - Messina, Chiara

AU - Nanni, Mauro

AU - Diverio, Daniela

AU - Biondi, Andrea

AU - Pession, Andrea

AU - Locatelli, Franco

AU - Piciocchi, Alfonso

AU - Gottardi, Enrico

AU - Saglio, Giuseppe

AU - Foà, Robin

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Imatinib mesylate (IM) is used for the management of childhood chronic myeloid leukaemia (CML). The most effective dosage of IM and its long-term efficacy in children are not well defined. The purpose of this multicentre study is to report on the long-term results of high-dose IM (340 mg/m2 /d) in CML patients in chronic phase (CP-CML) aged

AB - Imatinib mesylate (IM) is used for the management of childhood chronic myeloid leukaemia (CML). The most effective dosage of IM and its long-term efficacy in children are not well defined. The purpose of this multicentre study is to report on the long-term results of high-dose IM (340 mg/m2 /d) in CML patients in chronic phase (CP-CML) aged

KW - BCR-ABL1

KW - childhood

KW - chronic myeloid leukaemia

KW - imatinib

KW - tyrosine kinase inhibitors

UR - http://www.scopus.com/inward/record.url?scp=84942103657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942103657&partnerID=8YFLogxK

U2 - 10.1111/bjh.13453

DO - 10.1111/bjh.13453

M3 - Article

C2 - 25891192

AN - SCOPUS:84942103657

VL - 170

SP - 398

EP - 407

JO - British Journal of Haematology

JF - British Journal of Haematology

SN - 0007-1048

IS - 3

ER -

Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this