Long-term results of the surgical treatment of craniopharyngioma: The experience at the Policlinico Gemelli, Catholic University, Rome

M. Caldarelli, L. Massimi, G. Tamburrini, M. Cappa, C. Di Rocco

Research output: Contribution to journalArticle

Abstract

Background: Craniopharyngioma (CP) is the most common intracranial non-glial tumour observed in pediatric age. Although histologically benign and amenable to surgical treatment, its location and relation with vital nervous and vascular structures makes the feasibility of a radical resection difficult even in the microneurosurgery era. Beside the difficulties experienced when performing tumour resection, post-operative complications, such as endocrinological imbalance, represent another point that makes CP total excision a challenge. In order to avoid such complications, some authors have suggested to renounce to radical resection and to rely on post-operative radiation therapy to minimise the risk of residual tumour progression. Methods: We report our experience with 52 children and adolescents operated on for CP at the Department of Pediatrics, Section of Pediatric Neurosurgery, Catholic University Medical School, Rome, between January 1985 and December 2002. The study included 14 children

Original languageEnglish
Pages (from-to)747-757
Number of pages11
JournalChild's Nervous System
Volume21
Issue number8-9
DOIs
Publication statusPublished - Aug 2005

Keywords

  • Craniopharyngioma
  • Post-operative complications
  • Radical resection
  • Recurrence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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