Long-term study on symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipients

Maurizia Debiaggi, Filippo Canducci, Cristina Terulla, Michela Sampaolo, Maria Chiara Marinozzi, Paolo Emilio Alessandrino, Anna Amelia Colombo, Daniela Caldera, Letizia Zenone Bragotti, Roberta Migliavacca, Emanuela Bianchi, Egidio Romero, Massimo Clementi

Research output: Contribution to journalArticle

Abstract

From October 2004 through October 2006 a study was performed to evaluate the prevalence of human Metapneumovirus (hMPV) infection in adult hematopoietic stem cell transplant (HSCT) recipients. Sequential nasopharyngeal aspirates (NPA) were collected independently from respiratory symptoms and evaluated for hMPV-RNA by polymerase chain reaction (PCR) and sequence analysis. Results indicate epidemiological and molecular differences between the 2004-2005 and 2005-2006 periods and that hMPV seems not to symptomatically affect HSCT patients or cause late respiratory sequelae. In addition, data collected suggest a hospital origin of hMPV infection in most HSCT patients during the 2004-2005 period.

Original languageEnglish
Pages (from-to)255-258
Number of pages4
JournalNew Microbiologica
Volume30
Issue number3
Publication statusPublished - Jul 2007

Keywords

  • Acute respiratory disease
  • Hematopoietic stem cell transplantation
  • Human metapneumovirus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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