Long term survival analysis: Breast cancer and age at diagnosis

E. Marubini, G. Mezzanotte, P. Boracchi, U. Veronesi

Research output: Contribution to journalArticlepeer-review


The role of age at surgery of breast cancer patients as a determinant of relative survival after making allowance for clinical profile was investigated on a case series of 716 women followed for more than 20 years in one single institution. Multiplicative and additive models for grouped data were adopted to model the standardized mortality ratio and the excess death rate respectively. The models were fitted by the GLIM system assuming a Poisson error function. We conclude that operable breast cancer has a relatively lower impact on total mortality in older patients (65 years or more) than in younger ones and, moreover, the older patients have a more favourable course.

Original languageEnglish
Pages (from-to)737-748
Number of pages12
JournalStatistics in Medicine
Issue number7
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Epidemiology


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