Long-term survival in a patient with supratentorial glioblastoma: Clinical considerations

L. Cervoni, P. Celli, M. Salvati

Research output: Contribution to journalArticlepeer-review


Glioblastoma, a malignant tumor of neuroepithelial origin, is relatively uncommon in childhood, during which it accounts for 7%-9% of brain tumors. A few patients (about 3%) live more than 5 years. We report a 13-year-old girl who was admitted because one month earlier she had begun to present headache and diplopia. Brain computed tomography (CT) showed a right frontal tumor. At operation, complete excision of the visible tumor was performed. Histologic examination showed that the tumor was a glioblastoma multiforme. The patient underwent 52 Gy of external beam radiotherapy to the enhancing tumor mass plus 3-cm border, and chemotherapy with nitrosourea (BCNU). Fourteen years, 9 months later, the patient presents neither neurological deficits nor radiological relapse. We confirm that younger age, the one immutable prognostic factor, supports a particularly aggressive approach to the treatment of glioblastomas.

Original languageEnglish
Pages (from-to)221-224
Number of pages4
JournalItalian Journal of Neurological Sciences
Issue number4
Publication statusPublished - 1998


  • Glioblastoma multiforme
  • Long-term survival

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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