Long-term survival in patients with supratentorial glioblastoma

Maurizio Salvati, Luigi Cervoni, Marco Artico, Riccardo Caruso, Franco Maria Gagliardi

Research output: Contribution to journalArticlepeer-review


The authors report 11 patients with cerebral glioblastoma who lived at least 5 years after their initial diagnosis. There were 6 female and 5 male; the mean age was 39 years (range 24-55 years). All patients were treated surgically and postoperatively received whole-brain radiotherapy and chemotherapy. Five patients (45%) presented local recurrences after an average interval of 3.9 years from treatment. At average follow-up of 9 years (range 5-14 years), 7 patients (64%) were alive after an average interval of 8.1 years; 4 patients (36%) died from local relapse. Survival was influenced by patient age and, to a lesser degree, by treatment. A review of the literature, together with our own series, suggest that death from recurrence disease is unusual in glioblastoma patients who survive more than 5 years.

Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalJournal of Neuro-Oncology
Issue number1
Publication statusPublished - 1998


  • Glioblastoma multiforme
  • Long-term survival

ASJC Scopus subject areas

  • Clinical Neurology
  • Cancer Research
  • Oncology
  • Neuroscience(all)


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