TY - JOUR
T1 - Longitudinal changes of bone ultrasound measurements in healthy infants during the first year of life
T2 - Influence of gender and type of feeding
AU - Zuccotti, Gianvincenzo
AU - Viganò, Alessandra
AU - Cafarelli, Laura
AU - Pivetti, Valentina
AU - Pogliani, Laura
AU - Puzzovio, Maria
AU - Mora, Stefano
PY - 2011/10
Y1 - 2011/10
N2 - There is evidence suggesting that early events in life may predispose the adult to osteoporosis. We assessed bone status by quantitative ultrasonography in healthy neonates, and we report the changes occurring during the first year of life, according to the type of early feeding. We measured the speed of sound (SOS) of the left tibia in 116 full-term infants (0-9 days of age) and in their mothers (21-42 years of age). SOS values did not correlate with gestational age of the study subjects (r = 0.08) or anthropometric measurements. The SOS measurements of the mothers did not correlate with those of their children (r = 0.01). Fifty-seven infants had SOS measurements performed at 4 and 12 months. Twenty-five infants were exclusively breast-fed, 12 received formula milk from birth, and 20 received human and formula milk. SOS measurements at 4 months were comparable with those at baseline, whereas at 12 months they were significantly higher. No effect of type of feeding was observed, indicating that SOS changes may be independent of the type of early diet.
AB - There is evidence suggesting that early events in life may predispose the adult to osteoporosis. We assessed bone status by quantitative ultrasonography in healthy neonates, and we report the changes occurring during the first year of life, according to the type of early feeding. We measured the speed of sound (SOS) of the left tibia in 116 full-term infants (0-9 days of age) and in their mothers (21-42 years of age). SOS values did not correlate with gestational age of the study subjects (r = 0.08) or anthropometric measurements. The SOS measurements of the mothers did not correlate with those of their children (r = 0.01). Fifty-seven infants had SOS measurements performed at 4 and 12 months. Twenty-five infants were exclusively breast-fed, 12 received formula milk from birth, and 20 received human and formula milk. SOS measurements at 4 months were comparable with those at baseline, whereas at 12 months they were significantly higher. No effect of type of feeding was observed, indicating that SOS changes may be independent of the type of early diet.
KW - Bone mass
KW - Infant
KW - Quantitative ultrasonometry
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U2 - 10.1007/s00223-011-9520-2
DO - 10.1007/s00223-011-9520-2
M3 - Article
C2 - 21822923
AN - SCOPUS:82755172367
VL - 89
SP - 312
EP - 317
JO - Calcified Tissue International
JF - Calcified Tissue International
SN - 0171-967X
IS - 4
ER -