Longitudinal evaluation of leukoaraiosis with whole brain ADC histograms

M. Mascalchi, M. Moretti, R. Della Nave, F. Lolli, C. Tessa, G. Carlucci, L. Bartolini, G. Pracucci, L. Pantoni, M. Filippi, D. Inzitari

Research output: Contribution to journalArticlepeer-review

Abstract

FLAIR and diffusion-weighted MRI were obtained twice (mean interval 20 ± 4 months) in 10 patients with leukoaraiosis. At follow-up, visual extension of leukoaraiosis was unchanged, whereas the median of whole brain apparent diffusion coefficient (WB-ADC) histogram was increased (p = 0.008) and brain volume index (BVI) was decreased (p = 0.006). WB-ADC histogram and BVI are sensitive to leukoaraiosis and might be considered for monitoring progression of the disease.

Original languageEnglish
Pages (from-to)938-940
Number of pages3
JournalNeurology
Volume59
Issue number6
Publication statusPublished - Sep 24 2002

ASJC Scopus subject areas

  • Neuroscience(all)

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