Abstract
Twenty patients with human immunodeficiency virus type 1 (HIV-1) infection for >7 years, no HIV-1-related symptoms, no treatment, and CD4+ cell counts >500/μL were included in a prospective study in 1993. Four years later, 12 patients had progressed (SPs), while 8 had not (long-term nonprogressors [LTNPs]). At inclusion, HIV-1 RNA, but not DNA, levels were higher in SPs. During follow-up, a consistent increase in HIV-1 RNA was seen in only 1 LTNP. In 2 LTNPs, plasma viremia was persistently undetectable or
| Original language | English |
|---|---|
| Pages (from-to) | 1542-1548 |
| Number of pages | 7 |
| Journal | Journal of Infectious Diseases |
| Volume | 179 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Immunology
- Public Health, Environmental and Occupational Health
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Longitudinal quantification of human immunodeficiency virus type 1 DNA and RNA in long-term nonprogressors. / Broström, Christina; Visco-Comandini, Ubaldo; Yun, Zhibing; Sönnerborg, Anders.
In: Journal of Infectious Diseases, Vol. 179, No. 6, 1999, p. 1542-1548.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Longitudinal quantification of human immunodeficiency virus type 1 DNA and RNA in long-term nonprogressors
AU - Broström, Christina
AU - Visco-Comandini, Ubaldo
AU - Yun, Zhibing
AU - Sönnerborg, Anders
PY - 1999
Y1 - 1999
N2 - Twenty patients with human immunodeficiency virus type 1 (HIV-1) infection for >7 years, no HIV-1-related symptoms, no treatment, and CD4+ cell counts >500/μL were included in a prospective study in 1993. Four years later, 12 patients had progressed (SPs), while 8 had not (long-term nonprogressors [LTNPs]). At inclusion, HIV-1 RNA, but not DNA, levels were higher in SPs. During follow-up, a consistent increase in HIV-1 RNA was seen in only 1 LTNP. In 2 LTNPs, plasma viremia was persistently undetectable or
AB - Twenty patients with human immunodeficiency virus type 1 (HIV-1) infection for >7 years, no HIV-1-related symptoms, no treatment, and CD4+ cell counts >500/μL were included in a prospective study in 1993. Four years later, 12 patients had progressed (SPs), while 8 had not (long-term nonprogressors [LTNPs]). At inclusion, HIV-1 RNA, but not DNA, levels were higher in SPs. During follow-up, a consistent increase in HIV-1 RNA was seen in only 1 LTNP. In 2 LTNPs, plasma viremia was persistently undetectable or
UR - http://www.scopus.com/inward/record.url?scp=0032995567&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032995567&partnerID=8YFLogxK
U2 - 10.1086/314757
DO - 10.1086/314757
M3 - Article
C2 - 10228079
AN - SCOPUS:0032995567
VL - 179
SP - 1542
EP - 1548
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
SN - 0022-1899
IS - 6
ER -