Objective. Strain and strain rate imaging have emerged as modern echocardiographic technique to estimate myocardial deformation and rate of deformation. Evidences about changes in strain and strain rate occurring with senescence are poor. Aim of our study was to verify the existence of age-related modifications of systolic strain and strain rate in adults and elderly without ischemic heart disease and with normal ejection fraction. Methods. We studied 50 patients: 25 elderly and 25 adults, admitted at our Institute. All patients had complete clinical examination, electrocardiogram and laboratory tests. In every subject we performed standard echocardiographic examination with longitudinal 2D strain and strain rate analysis of the 6 myocardial segments detectable in apical four-chamber view. Results. Old patients have lower values of longitudinal systolic strain and strain rate for almost all examined myocardial segments. Mean strain was significantly lower in elderly compared with adults (-19,70 ± 3,46 vs. -21,64 ± 2,48; p: 0,027), as it was the case for mean strain rate (-1,20 ± 0,22 vs. -1,34 ± 0,19; p: 0,023). Linear regression identified age as the only predictor of mean strain, explaining about 22% of variability; indexed left ventricular mass was the only predictor of mean strain rate accounting for 19% of variability. Conclusions. Lower strain and strain rate values in elderly appear congruent with age-related structural and functional changes reducing myocardial contractility. Strain and strain rate imaging is a technique of significant value enabling assessment of segmental myocardial function and completing information derived from global function indexes.
|Translated title of the contribution||Longitudinal systolic strain and strain rate analysis in adult and elderly patients|
|Number of pages||10|
|Journal||Giornale di Gerontologia|
|Publication status||Published - Oct 2009|
ASJC Scopus subject areas
- Geriatrics and Gerontology