Loss of β-arrestin-2 gene and possible functional consequences on Sezary Syndrome

Cristina Cristofoletti, Antonella Bresin, Elisabetta Caprini, Giandomenico Russo, Maria Grazia Narducci

Research output: Contribution to journalArticle


Sezary Syndrome is an aggressive T-cell Lymphoma involving blood, skin and lymphonodes Involvement of the CXCR4-SDF1 has been previously shown. We here present evidence also of the involvement of B-arrestin a downstream regulator of CXCR4, that is depleted and downregulated as well as a potential functional role for this depletion.

Original languageEnglish
Pages (from-to)1292-1294
Number of pages3
JournalCell Cycle
Issue number11
Publication statusPublished - Jun 2019


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