Loss of β-arrestin-2 gene and possible functional consequences on Sezary Syndrome

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Abstract

Sezary Syndrome is an aggressive T-cell Lymphoma involving blood, skin and lymphonodes Involvement of the CXCR4-SDF1 has been previously shown. We here present evidence also of the involvement of B-arrestin a downstream regulator of CXCR4, that is depleted and downregulated as well as a potential functional role for this depletion.

Original languageEnglish
Pages (from-to)1292-1294
Number of pages3
JournalCell Cycle
Volume18
Issue number11
DOIs
Publication statusPublished - Jun 2019

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