Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes

L. Moretta; M. C. Mingari; C. Romanzi

Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes

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Abstract

The authors report here that interaction between IgG immune complexes and IgG-Fc receptors present on human T.(G) cells is followed by the irreversible disappearance of the Fc receptors. As a consequence of this 'modulation' T.(G) lymphocytes lose most of their cytotoxic activity in an antibody-mediated cell killing system.

Original language	English
Pages (from-to)	618-62O
Journal	Nature
Volume	272
Issue number	5654
Publication status	Published - 1978

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title = "Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes",

abstract = "The authors report here that interaction between IgG immune complexes and IgG-Fc receptors present on human T.(G) cells is followed by the irreversible disappearance of the Fc receptors. As a consequence of this 'modulation' T.(G) lymphocytes lose most of their cytotoxic activity in an antibody-mediated cell killing system.",

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year = "1978",

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AU - Moretta, L.

AU - Mingari, M. C.

AU - Romanzi, C.

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AB - The authors report here that interaction between IgG immune complexes and IgG-Fc receptors present on human T.(G) cells is followed by the irreversible disappearance of the Fc receptors. As a consequence of this 'modulation' T.(G) lymphocytes lose most of their cytotoxic activity in an antibody-mediated cell killing system.

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JF - Nature

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IS - 5654

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Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes

Abstract

ASJC Scopus subject areas

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