Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes

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Abstract

The authors report here that interaction between IgG immune complexes and IgG-Fc receptors present on human T.(G) cells is followed by the irreversible disappearance of the Fc receptors. As a consequence of this 'modulation' T.(G) lymphocytes lose most of their cytotoxic activity in an antibody-mediated cell killing system.

Original languageEnglish
Pages (from-to)618-62O
JournalNature
Volume272
Issue number5654
Publication statusPublished - 1978

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Fc Receptors
Antigen-Antibody Complex
Immunoglobulin G
T-Lymphocytes
IgG Receptors
Gastrin-Secreting Cells
Lymphocytes
Antibodies

ASJC Scopus subject areas

  • General

Cite this

Loss of fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes. / Moretta, L.; Mingari, M. C.; Romanzi, C.

In: Nature, Vol. 272, No. 5654, 1978, p. 618-62O.

Research output: Contribution to journalArticle

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