Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies

Giovanni Rizzo, Roberto De Blasi, Rosa Capozzo, Rosanna Tortelli, Maria Rosaria Barulli, Rocco Liguori, Daniela Grasso, Giancarlo Logroscino

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalJournal of Alzheimer's Disease
Volume67
Issue number1
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Swallows
Lewy Body Disease
Tail
Frontotemporal Dementia
Substantia Nigra
Deglutition
Alzheimer Disease
Sensitivity and Specificity

Keywords

  • Dementia with Lewy bodies
  • magnetic resonance imaging
  • nigrosome
  • susceptibility-weighted imaging
  • swallow tail sign

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies. / Rizzo, Giovanni; De Blasi, Roberto; Capozzo, Rosa; Tortelli, Rosanna; Barulli, Maria Rosaria; Liguori, Rocco; Grasso, Daniela; Logroscino, Giancarlo.

In: Journal of Alzheimer's Disease, Vol. 67, No. 1, 01.01.2019, p. 61-65.

Research output: Contribution to journalArticle

Rizzo, G, De Blasi, R, Capozzo, R, Tortelli, R, Barulli, MR, Liguori, R, Grasso, D & Logroscino, G 2019, 'Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies', Journal of Alzheimer's Disease, vol. 67, no. 1, pp. 61-65. https://doi.org/10.3233/JAD-180687
Rizzo, Giovanni ; De Blasi, Roberto ; Capozzo, Rosa ; Tortelli, Rosanna ; Barulli, Maria Rosaria ; Liguori, Rocco ; Grasso, Daniela ; Logroscino, Giancarlo. / Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies. In: Journal of Alzheimer's Disease. 2019 ; Vol. 67, No. 1. pp. 61-65.
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