Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies

Giovanni Rizzo, Roberto De Blasi, Rosa Capozzo, Rosanna Tortelli, Maria Rosaria Barulli, Rocco Liguori, Daniela Grasso, Giancarlo Logroscino

Research output: Contribution to journalArticle

Abstract

We assessed nigral dorsolateral hyperintensity (swallow tail sign) at susceptibility-weighted imaging using 3T-MRI in 15 dementia with Lewy bodies (DLB), 11 Alzheimer's disease (AD), and 8 frontotemporal dementia (FTD) patients and 10 subjects with subjective memory complaint (SMC). More DLB patients lacked nigral hyperintesity (p<0.05). Sensitivity, specificity, and accuracy of DLB diagnosis were, respectively: 80, 64, and 73 versus AD; 80, 75, and 78 versus FTD; and 80, 90, and 84 versus SMC. Considering bilateral loss, sensitivity decreased (53) but specificity increased (82-100). Swallow tail sign loss, especially if bilateral, can be useful for DLB diagnosis.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalJournal of Alzheimer's Disease
Volume67
Issue number1
DOIs
Publication statusPublished - Jan 1 2019

Keywords

  • Dementia with Lewy bodies
  • magnetic resonance imaging
  • nigrosome
  • susceptibility-weighted imaging
  • swallow tail sign

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Loss of Swallow Tail Sign on Susceptibility-Weighted Imaging in Dementia with Lewy Bodies'. Together they form a unique fingerprint.

Cite this