Loss of temporal retinal nerve fibers in Parkinson disease: A mitochondrial pattern?

C. La Morgia, P. Barboni, G. Rizzo, M. Carbonelli, G. Savini, C. Scaglione, S. Capellari, S. Bonazza, M. P. Giannoccaro, G. Calandra-Buonaura, R. Liguori, P. Cortelli, P. Martinelli, A. Baruzzi, V. Carelli

Research output: Contribution to journalArticle

Abstract

Background and purpose: Optic nerve involvement is frequent in mitochondrial disease, and retinal abnormalities are described in Parkinson's disease (PD). Methods: We evaluated retinal nerve fiber layer (RNFL) thickness by optical coherence tomography in 43 patients with PD and in 86 age-matched controls. We considered separately the eyes ipsilateral and contralateral to the most affected body side in patients with PD. ancova analysis, Pearson test, and multiple regression analysis were used (P

Original languageEnglish
Pages (from-to)198-201
Number of pages4
JournalEuropean Journal of Neurology
Volume20
Issue number1
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Mitochondrial disorders
  • Optic nerve
  • Optical coherence tomography
  • Parkinson's disease
  • Retina

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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