Abstract
Background Intraoperative fluorescein detection has been used in the fields of vascular and oncologic neurosurgery since 1948. Modifications of the optics in order to enhance the fluorescence contrast under microscopic view have been developed by many authors. The industries, during the past 10 years, provided commercial high-cost optimized apparatuses. Reviewing the literature, we found that the prototypical techniques were definitely inexpensive but lacked reliability, reproducibility, and standard legal norms. Methods We describe the developing of a fluorescein detection system that could be economic, simple, effective, and law abiding. Results We employed a commercial violet-blue filter designed for fluorescein excitation in endoscopic procedures and used commercial photographic yellow optical filters for fluorescence detection. All the instrumentation is cleared for clinical use, and its cost is up to 200 times lower than commercial apparatuses. Conclusion Our results show a good distinction of fluorescein-stained structures, with overall acceptable operating light conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 54-58 |
| Number of pages | 5 |
| Journal | World Neurosurgery |
| Volume | 88 |
| DOIs | |
| Publication status | Published - Apr 1 2016 |
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Keywords
- Filter
- Fluorescein
- Glioma
- Key words Endoscopy
- Low-cost
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
Cite this
Low-Cost Fluorescein Detection System for High-Grade Glioma Surgery. / Bongetta, Daniele; Zoia, Cesare; Pugliese, Raffaelino; Adinolfi, Daniela; Silvani, Vittorio; Gaetani, Paolo.
In: World Neurosurgery, Vol. 88, 01.04.2016, p. 54-58.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Low-Cost Fluorescein Detection System for High-Grade Glioma Surgery
AU - Bongetta, Daniele
AU - Zoia, Cesare
AU - Pugliese, Raffaelino
AU - Adinolfi, Daniela
AU - Silvani, Vittorio
AU - Gaetani, Paolo
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Background Intraoperative fluorescein detection has been used in the fields of vascular and oncologic neurosurgery since 1948. Modifications of the optics in order to enhance the fluorescence contrast under microscopic view have been developed by many authors. The industries, during the past 10 years, provided commercial high-cost optimized apparatuses. Reviewing the literature, we found that the prototypical techniques were definitely inexpensive but lacked reliability, reproducibility, and standard legal norms. Methods We describe the developing of a fluorescein detection system that could be economic, simple, effective, and law abiding. Results We employed a commercial violet-blue filter designed for fluorescein excitation in endoscopic procedures and used commercial photographic yellow optical filters for fluorescence detection. All the instrumentation is cleared for clinical use, and its cost is up to 200 times lower than commercial apparatuses. Conclusion Our results show a good distinction of fluorescein-stained structures, with overall acceptable operating light conditions.
AB - Background Intraoperative fluorescein detection has been used in the fields of vascular and oncologic neurosurgery since 1948. Modifications of the optics in order to enhance the fluorescence contrast under microscopic view have been developed by many authors. The industries, during the past 10 years, provided commercial high-cost optimized apparatuses. Reviewing the literature, we found that the prototypical techniques were definitely inexpensive but lacked reliability, reproducibility, and standard legal norms. Methods We describe the developing of a fluorescein detection system that could be economic, simple, effective, and law abiding. Results We employed a commercial violet-blue filter designed for fluorescein excitation in endoscopic procedures and used commercial photographic yellow optical filters for fluorescence detection. All the instrumentation is cleared for clinical use, and its cost is up to 200 times lower than commercial apparatuses. Conclusion Our results show a good distinction of fluorescein-stained structures, with overall acceptable operating light conditions.
KW - Filter
KW - Fluorescein
KW - Glioma
KW - Key words Endoscopy
KW - Low-cost
UR - http://www.scopus.com/inward/record.url?scp=84959498266&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959498266&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2016.01.017
DO - 10.1016/j.wneu.2016.01.017
M3 - Article
C2 - 26802869
AN - SCOPUS:84959498266
VL - 88
SP - 54
EP - 58
JO - World Neurosurgery
JF - World Neurosurgery
SN - 1878-8750
ER -