Low dosage cidofovir without probenecid as treatment for bk virus hamorrhagic cystitis after hemopoietic stem cell transplant

Maura Faraci, Daniela Cuzzubbo, Edoardo Lanino, Eddi Di Marco, Carmela Cirillo, Sandro Dallorso, Giuseppe Morreale, Cristina Moroni, Elio Castagnola

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a single-center pediatric experience with 1 mg/kg/wk cidofovir without probenecid in 7 children with BK virus-associated hemorrhagic cystitis. Clinical improvement was observed in all cases, without adverse events, although significant reduction of urinary viral load was observed 2 weeks after the end of cidofovir in 5 out of 6 patients who completed the treatment.

Original languageEnglish
Pages (from-to)55-57
Number of pages3
JournalPediatric Infectious Disease Journal
Volume28
Issue number1
DOIs
Publication statusPublished - Jan 2009

Keywords

  • BK virus
  • cidofovir
  • hemorrhagic cystitis
  • probenecid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

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