Abstract
Objectives - The aim of this study was to investigate the clinical efficacy of clozapine, an atypical neuroleptic, on L-dopa induced dyskinesias of Parkinson's disease. Material and methods -In an open study, a group of 10 PD patients was treated with low dosage clozapine (mean 30 mg/day) for a 4- month period and L-dopa dyskinesias were evaluated in basal conditions and during clozapine treatment after the usual morning dose of clozapine. We utilized the AIMS for evaluation of dyskinesias and UPDRS for the assessment of motor performances. Results - Clozapine produced a significant (P
| Original language | English |
|---|---|
| Pages (from-to) | 295-299 |
| Number of pages | 5 |
| Journal | Acta Neurologica Scandinavica |
| Volume | 97 |
| Issue number | 5 |
| Publication status | Published - 1998 |
Keywords
- Clozapine
- Dyskinesias
- Parkinson's disease
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)