Abstract
Objective: In 55 prepubertal children with growth failure, aged 8.62 ± 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately. Patients and Methods: The patients were randomly divided into two groups: group A consisting of 37 children received 0.05 U/kg insulin, while group B consisting of 18 patients received 0.1 U/kg insulin. Each child received the same dose of arginine per kg during the second test. Results: Serum growth hormone (GH) peak levels were significantly (p
| Original language | English |
|---|---|
| Pages (from-to) | 815-818 |
| Number of pages | 4 |
| Journal | Journal of Pediatric Endocrinology and Metabolism |
| Volume | 18 |
| Issue number | 8 |
| Publication status | Published - Aug 2005 |
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Keywords
- Children
- Cortisol
- Glycaemia
- Growth hormone
- Growth hormone deficiency
- Insulin
ASJC Scopus subject areas
- Endocrinology
- Pediatrics, Perinatology, and Child Health
Cite this
Bozzola, M., Comoli, P., Bozzola, E., Tinelli, C., Marello, A., Stabile, M., Mazzola, A., & Locatelli, V. (2005). Low dose of insulin for assessment of growth hormone and cortisol release in short children. Journal of Pediatric Endocrinology and Metabolism, 18(8), 815-818.