Low dose of insulin for assessment of growth hormone and cortisol release in short children

Mauro Bozzola; Patrizia Comoli; Elena Bozzola; Carmine Tinelli; Annalisa Marello; Milena Stabile; Alessandra Mazzola; Vittorio Locatelli

Low dose of insulin for assessment of growth hormone and cortisol release in short children

Mauro Bozzola, Patrizia Comoli, Elena Bozzola, Carmine Tinelli, Annalisa Marello, Milena Stabile, Alessandra Mazzola, Vittorio Locatelli

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: In 55 prepubertal children with growth failure, aged 8.62 ± 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately. Patients and Methods: The patients were randomly divided into two groups: group A consisting of 37 children received 0.05 U/kg insulin, while group B consisting of 18 patients received 0.1 U/kg insulin. Each child received the same dose of arginine per kg during the second test. Results: Serum growth hormone (GH) peak levels were significantly (p

Original language	English
Pages (from-to)	815-818
Number of pages	4
Journal	Journal of Pediatric Endocrinology and Metabolism
Volume	18
Issue number	8
Publication status	Published - Aug 2005

Keywords

Children
Cortisol
Glycaemia
Growth hormone
Growth hormone deficiency
Insulin

ASJC Scopus subject areas

Endocrinology
Pediatrics, Perinatology, and Child Health

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Low dose of insulin for assessment of growth hormone and cortisol release in short children. / Bozzola, Mauro; Comoli, Patrizia ; Bozzola, Elena ; Tinelli, Carmine; Marello, Annalisa; Stabile, Milena; Mazzola, Alessandra; Locatelli, Vittorio.

In: Journal of Pediatric Endocrinology and Metabolism, Vol. 18, No. 8, 08.2005, p. 815-818.

Research output: Contribution to journal › Article › peer-review

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abstract = "Objective: In 55 prepubertal children with growth failure, aged 8.62 ± 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately. Patients and Methods: The patients were randomly divided into two groups: group A consisting of 37 children received 0.05 U/kg insulin, while group B consisting of 18 patients received 0.1 U/kg insulin. Each child received the same dose of arginine per kg during the second test. Results: Serum growth hormone (GH) peak levels were significantly (p ",

keywords = "Children, Cortisol, Glycaemia, Growth hormone, Growth hormone deficiency, Insulin",

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AU - Bozzola, Mauro

AU - Comoli, Patrizia

AU - Bozzola, Elena

AU - Tinelli, Carmine

AU - Marello, Annalisa

AU - Stabile, Milena

AU - Mazzola, Alessandra

AU - Locatelli, Vittorio

PY - 2005/8

Y1 - 2005/8

N2 - Objective: In 55 prepubertal children with growth failure, aged 8.62 ± 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately. Patients and Methods: The patients were randomly divided into two groups: group A consisting of 37 children received 0.05 U/kg insulin, while group B consisting of 18 patients received 0.1 U/kg insulin. Each child received the same dose of arginine per kg during the second test. Results: Serum growth hormone (GH) peak levels were significantly (p

AB - Objective: In 55 prepubertal children with growth failure, aged 8.62 ± 2.89 years, we evaluated the efficacy of a test using only half the usual dose of insulin by comparing the results with those obtained during a classical arginine tolerance test, performed separately. Patients and Methods: The patients were randomly divided into two groups: group A consisting of 37 children received 0.05 U/kg insulin, while group B consisting of 18 patients received 0.1 U/kg insulin. Each child received the same dose of arginine per kg during the second test. Results: Serum growth hormone (GH) peak levels were significantly (p

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KW - Cortisol

KW - Glycaemia

KW - Growth hormone

KW - Growth hormone deficiency

KW - Insulin

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Low dose of insulin for assessment of growth hormone and cortisol release in short children

Abstract

Keywords

ASJC Scopus subject areas

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