Low doses of α 2B interferon in the treatment of hairy cell leukemia: Results of treatment and mean follow-up at 18 months in 13 patients

G. Santagati, G. Nastasi, C. Porta, M. Moroni, C. Santagati, I. Casagranda, E. Bobbio-Pallavicini, M. F. Cosimi

Research output: Contribution to journalArticle

Abstract

We treated 13 Hairy Cell Leukemia patients with rIFN α 2b. In case of complete/partial response, the patients were submitted to maintenance treatment, while, in case of minimal/no response, a second induction cycle was administered, followed by a maintenance one. The patients were followed, on an outpatients basis, for 18 months at least obtaining a 100% overall response rate; one patient had complete response, 7 had partial response, and 5 only minimal response. Six patients (46%) relapsed an average of 13 months after the end of the treatment. The utility of a maintenance therapy is discussed.

Original languageEnglish
Pages (from-to)66-69
Number of pages4
JournalPathologica
Volume86
Issue number1
Publication statusPublished - 1994

Keywords

  • α interferon
  • disease stabilization
  • hairy cell leukemia
  • maintenance therapy
  • response rates

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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    Santagati, G., Nastasi, G., Porta, C., Moroni, M., Santagati, C., Casagranda, I., Bobbio-Pallavicini, E., & Cosimi, M. F. (1994). Low doses of α 2B interferon in the treatment of hairy cell leukemia: Results of treatment and mean follow-up at 18 months in 13 patients. Pathologica, 86(1), 66-69.