The authors describe a new form of mechanical pulmonary ventilation, low-frequency positive pressure ventilation with extracorporeal CO 2 removal (LFPPV-ECCO 2R). In a series of animal studies the rate of mechanical ventilation was 0.66, 1, 2, and 4 min -1 at a tidal volume of 3, 10, and 15 ml kg -1. It was possible to maintain normal blood gases and normal lung volumes and lung mechanics even at the lowest ventilator rate with tidal volumes of 10 or 15 ml kg -1. Each experiment lasted 7 hr.
|Number of pages||8|
|Journal||Anesthesia and Analgesia|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine