Low glomerular filtration in the population: Prevalence, associated disorders, and awareness

M. Cirillo, M. Laurenzi, M. Mancini, A. Zanchetti, C. Lombardi, N. G. De Santo

Research output: Contribution to journalArticle

Abstract

Estimated glomerular filtration rate (eGFR) was used for analysis of kidney disease prevalence in the United States. The study investigated on prevalence, associated disorders, and kidney disease awareness in an Italian population sample. Data were collected on serum creatinine, other laboratory indices, blood pressure, and medical history in the Gubbio Population Study (n=4574, both sexes, ages 18-95 years). Analyses were carried out on eGFR (equation of Modification Diet in Renal Disease study), disorders potentially secondary to kidney dysfunction (hypertension, high serum uric acid, high serum phosphorus/low serum calcium, high serum potassium, cardiovascular disease, anemia), and kidney disease awareness. The prevalence of eGFR 2 increased with age in both sexes (from 30% for ages ≥75 years, P2, number of disorders secondary to kidney dysfunction was ≥2 in the majority of persons, was higher than in persons with eGFR ≥60 ml/min × 1.73 m2 (P2 and directly related to serum creatinine and number of disorders secondary to kidney dysfunction (P

Original languageEnglish
Pages (from-to)800-806
Number of pages7
JournalKidney International
Volume70
Issue number4
DOIs
Publication statusPublished - Aug 28 2006

Keywords

  • Albuminuria
  • Epidemiology and outcomes
  • Glomerular filtration rate
  • Kidney failure

ASJC Scopus subject areas

  • Nephrology

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