Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease

S. Piantoni, L. Andreoli, F. Allegri, P. L. Meroni, A. Tincani

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to assess vitamin D (vit. D) levels in patients with primary antiphospholipid syndrome (PAPS), the association between hypovitaminosis D and clinical manifestations, and the effect of vit. D supplementation on serum levels. Vit. D serum levels of 115 PAPS patients, classified according to the 2006 revised criteria at the Rheumatology Department, Brescia, and of 128 voluntary healthy donors (NHD) were tested in collaboration with DiaSorin (Saluggia, Italy) using the LIAISON® chemiluminescent immunoassay. Clinical data were derived from clinical charts. Vit. D deficiency was more prevalent in PAPS than NHD (17% vs 5%). During the summer, vit. D levels were lower in PAPS than NHD (median 28 vs 40.1 ng/mL, P

Original languageEnglish
Pages (from-to)307-313
Number of pages7
JournalReumatismo
Volume64
Issue number5
Publication statusPublished - 2012

Keywords

  • Primary antiphospholipid syndrome
  • Thrombosis
  • Vitamin D

ASJC Scopus subject areas

  • Rheumatology

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