Bassa prevalenza di anticorpi anti-virus dell'epatite E (anti-HEV) in pazienti emodializzati cronici: Studio sieroepidemiologico

Translated title of the contribution: Low prevalence of hepatitis E virus antibody in haemodialysis patients: A seroepidemiological study

F. Fabrizi, G. Lunghi, G. Bacchini, I. Guarnori, L. Raffaele, G. Erba, F. Locatelli

Research output: Contribution to journalArticle

Abstract

Hepatitis E virus (HEV) is the causative agent for enteric non-A, non-B hepatitis. Transmission is via the faecal route but the possibility of transmission by blood has been raised. Data concerning anti-HEV prevalence among chronic haemodialysis patients (HD) are scarce and give conflicting results. We tested for anti-HEV antibody 204 chronic HD patients attending a single dialysis unit. We found 6 anti-HEV positive patients, the anti-HEV prevalence was 2.9%. The prevalence rates of HBV and HCV infections were 39% and 22%, respectively. No anti-HEV positive patient showed past or current biochemical signs of liver disease, no risk factor for anti-HEV antibody was identified in most anti-HEV positive patients. In conclusion, our HD patients showed a low anti-HEV prevalence, there was no association between HEV and blood-borne infections (HBV, HCV and HIV) and the cases of anti-HEV positivity found by us were likely to be the result of a local infection by HEV. It seems that HD patients are not a risk group for HEV infection.

Translated title of the contributionLow prevalence of hepatitis E virus antibody in haemodialysis patients: A seroepidemiological study
Original languageItalian
Pages (from-to)227-232
Number of pages6
JournalGiornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
Volume13
Issue number4
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Nephrology

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