Low prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in urban and rural community settings in Bolivia and Peru

Alessandro Bartoloni, Lucia Pallecchi, Connie Fernandez, Antonia Mantella, Eleonora Riccobono, Donata Magnelli, Dario Mannini, Marianne Strohmeyer, Filippo Bartalesi, Higinio Segundo, Joaquin Monasterio, Hugo Rodriguez, César Cabezas, Eduardo Gotuzzo, Gian Maria Rossolini

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective: To investigate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage in rural and urban community settings of Bolivia and Peru. Methods: MRSA nasal carriage was investigated in 585 individuals living in rural and urban areas of Bolivia and Peru (one urban area, one small rural village, and two native communities, one of which was highly isolated). MRSA isolates were subjected to molecular analysis for the detection of virulence genes, characterization of the staphylococcal cassette chromosome mec (SCC. mec), and genotyping (multilocus sequence typing (MLST) and pulsed-field gel electrophoresis (PFGE)). Results: An overall very low prevalence of MRSA nasal carriage was observed (0.5%), with MRSA carriers being detected only in a small rural village of the Bolivian Chaco. The three MRSA isolates showed the characteristics of community-associated MRSA (being susceptible to all non-beta-lactam antibiotics and harboring the SCC. mec type IV), were clonally related, and belonged to ST1649. Conclusions: This study provides an insight into the epidemiology of MRSA in community settings of Bolivia and Peru. Reliable, time-saving, and low-cost methods should be implemented to encourage continued surveillance of MRSA dissemination in resource-limited countries.

Original languageEnglish
JournalInternational Journal of Infectious Diseases
Volume17
Issue number5
DOIs
Publication statusPublished - May 2013

Fingerprint

Bolivia
Peru
Rural Population
Methicillin-Resistant Staphylococcus aureus
Nose
Multilocus Sequence Typing
Lactams
Pulsed Field Gel Electrophoresis
Population Groups
Virulence
Epidemiology
Chromosomes
Anti-Bacterial Agents
Costs and Cost Analysis

Keywords

  • Bolivia
  • Community settings
  • Latin America
  • MRSA
  • Nasal carriage
  • Peru
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Low prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in urban and rural community settings in Bolivia and Peru. / Bartoloni, Alessandro; Pallecchi, Lucia; Fernandez, Connie; Mantella, Antonia; Riccobono, Eleonora; Magnelli, Donata; Mannini, Dario; Strohmeyer, Marianne; Bartalesi, Filippo; Segundo, Higinio; Monasterio, Joaquin; Rodriguez, Hugo; Cabezas, César; Gotuzzo, Eduardo; Rossolini, Gian Maria.

In: International Journal of Infectious Diseases, Vol. 17, No. 5, 05.2013.

Research output: Contribution to journalArticle

Bartoloni, A, Pallecchi, L, Fernandez, C, Mantella, A, Riccobono, E, Magnelli, D, Mannini, D, Strohmeyer, M, Bartalesi, F, Segundo, H, Monasterio, J, Rodriguez, H, Cabezas, C, Gotuzzo, E & Rossolini, GM 2013, 'Low prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in urban and rural community settings in Bolivia and Peru', International Journal of Infectious Diseases, vol. 17, no. 5. https://doi.org/10.1016/j.ijid.2012.11.017
Bartoloni, Alessandro ; Pallecchi, Lucia ; Fernandez, Connie ; Mantella, Antonia ; Riccobono, Eleonora ; Magnelli, Donata ; Mannini, Dario ; Strohmeyer, Marianne ; Bartalesi, Filippo ; Segundo, Higinio ; Monasterio, Joaquin ; Rodriguez, Hugo ; Cabezas, César ; Gotuzzo, Eduardo ; Rossolini, Gian Maria. / Low prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in urban and rural community settings in Bolivia and Peru. In: International Journal of Infectious Diseases. 2013 ; Vol. 17, No. 5.
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