Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovirRemtricitabine/lamivudineRefavirenz administered on a multiple tablet therapy

José L. Blanco, Julio S G Montaner, Vincent C. Marconi, Maria M. Santoro, Ariel E. Campos-Loza, Robert W. Shafer, Michael D. Miller, Roger Paredes, Richard Harrigan, Mihn L. Nguyen, Carlo F. Perno, Lucero A. Gonzalez-Hernandez, José M. Gatell

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Fixed-dose combination antiretroviral therapy administered as a singletablet regimen (STR) may improve virologic suppression rates. The effect of STRs on development of resistance when virologic failure occurs on STRs is not known.

Original languageEnglish
Pages (from-to)2531-2539
Number of pages9
JournalAIDS (London, England)
Volume28
Issue number17
DOIs
Publication statusPublished - 2014

Keywords

  • Antiretroviral treatment
  • Atripla
  • HIV-1 resistance
  • Single-tablet regimen

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases
  • Medicine(all)

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