Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovirRemtricitabine/lamivudineRefavirenz administered on a multiple tablet therapy

José L. Blanco, Julio S G Montaner, Vincent C. Marconi, Maria M. Santoro, Ariel E. Campos-Loza, Robert W. Shafer, Michael D. Miller, Roger Paredes, Richard Harrigan, Mihn L. Nguyen, Carlo F. Perno, Lucero A. Gonzalez-Hernandez, José M. Gatell

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background: Fixed-dose combination antiretroviral therapy administered as a singletablet regimen (STR) may improve virologic suppression rates. The effect of STRs on development of resistance when virologic failure occurs on STRs is not known.

Original languageEnglish
Pages (from-to)2531-2539
Number of pages9
JournalAIDS (London, England)
Volume28
Issue number17
DOIs
Publication statusPublished - 2014

Fingerprint

Drug Resistance
Tablets
Mutation
Therapeutics
Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination

Keywords

  • Antiretroviral treatment
  • Atripla
  • HIV-1 resistance
  • Single-tablet regimen

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases
  • Medicine(all)

Cite this

Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovirRemtricitabine/lamivudineRefavirenz administered on a multiple tablet therapy. / Blanco, José L.; Montaner, Julio S G; Marconi, Vincent C.; Santoro, Maria M.; Campos-Loza, Ariel E.; Shafer, Robert W.; Miller, Michael D.; Paredes, Roger; Harrigan, Richard; Nguyen, Mihn L.; Perno, Carlo F.; Gonzalez-Hernandez, Lucero A.; Gatell, José M.

In: AIDS (London, England), Vol. 28, No. 17, 2014, p. 2531-2539.

Research output: Contribution to journalArticle

Blanco, JL, Montaner, JSG, Marconi, VC, Santoro, MM, Campos-Loza, AE, Shafer, RW, Miller, MD, Paredes, R, Harrigan, R, Nguyen, ML, Perno, CF, Gonzalez-Hernandez, LA & Gatell, JM 2014, 'Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovirRemtricitabine/lamivudineRefavirenz administered on a multiple tablet therapy', AIDS (London, England), vol. 28, no. 17, pp. 2531-2539. https://doi.org/10.1097/QAD.0000000000000424
Blanco, José L. ; Montaner, Julio S G ; Marconi, Vincent C. ; Santoro, Maria M. ; Campos-Loza, Ariel E. ; Shafer, Robert W. ; Miller, Michael D. ; Paredes, Roger ; Harrigan, Richard ; Nguyen, Mihn L. ; Perno, Carlo F. ; Gonzalez-Hernandez, Lucero A. ; Gatell, José M. / Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovirRemtricitabine/lamivudineRefavirenz administered on a multiple tablet therapy. In: AIDS (London, England). 2014 ; Vol. 28, No. 17. pp. 2531-2539.
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