Abstract
Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.
| Original language | English |
|---|---|
| Pages (from-to) | 391-394 |
| Number of pages | 4 |
| Journal | Transplantation Proceedings |
| Volume | 48 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1 2016 |
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ASJC Scopus subject areas
- Surgery
- Transplantation
Cite this
Lung Allocation Score : A Single-Center Simulation. / Rosso, L.; Palleschi, A.; Tosi, D.; Mendogni, P.; Righi, I.; Carrinola, R.; Montoli, M.; Damarco, F.; Rossetti, V.; Morlacchi, L. C.; Nosotti, M.
In: Transplantation Proceedings, Vol. 48, No. 2, 01.03.2016, p. 391-394.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lung Allocation Score
T2 - A Single-Center Simulation
AU - Rosso, L.
AU - Palleschi, A.
AU - Tosi, D.
AU - Mendogni, P.
AU - Righi, I.
AU - Carrinola, R.
AU - Montoli, M.
AU - Damarco, F.
AU - Rossetti, V.
AU - Morlacchi, L. C.
AU - Nosotti, M.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.
AB - Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.
UR - http://www.scopus.com/inward/record.url?scp=84964493059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964493059&partnerID=8YFLogxK
U2 - 10.1016/j.transproceed.2015.12.058
DO - 10.1016/j.transproceed.2015.12.058
M3 - Article
AN - SCOPUS:84964493059
VL - 48
SP - 391
EP - 394
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 2
ER -