TY - JOUR
T1 - Lung Allocation Score
T2 - A Single-Center Simulation
AU - Rosso, L.
AU - Palleschi, A.
AU - Tosi, D.
AU - Mendogni, P.
AU - Righi, I.
AU - Carrinola, R.
AU - Montoli, M.
AU - Damarco, F.
AU - Rossetti, V.
AU - Morlacchi, L. C.
AU - Nosotti, M.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.
AB - Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.
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U2 - 10.1016/j.transproceed.2015.12.058
DO - 10.1016/j.transproceed.2015.12.058
M3 - Article
AN - SCOPUS:84964493059
VL - 48
SP - 391
EP - 394
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 2
ER -