Lung Allocation Score: A Single-Center Simulation

L. Rosso, A. Palleschi, D. Tosi, P. Mendogni, I. Righi, R. Carrinola, M. Montoli, F. Damarco, V. Rossetti, L. C. Morlacchi, M. Nosotti

Research output: Contribution to journalArticlepeer-review


Background The lung allocation score (LAS) was introduced in the United States in May 2005 with the main goal of reducing the waiting list mortality of patients with end-stage lung diseases, but also to enhance the lung transplant benefit and improve the management of urgent candidates. Several papers have reported that LAS resulted in a reduction of the waiting list mortality but no significant survival benefit was noted. Methods We evaluate the usefulness of LAS as a predictor for lung transplantation outcome in 123 patients listed for lung transplantation in an Italian center. Primary endpoints were waiting list mortality and posttransplant mortality at 1 year; secondary endpoints included perioperative circulatory support, cardiopulmonary bypass, primary graft dysfunction, and long-term survival after transplantation. Results We observed the absence of correlation between LAS and waiting list mortality. The LAS did not affect the long-term survival in our population. Conclusions High LAS was predictive of primary graft dysfunction of grade 3 in the first 72 hours after transplantation.

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalTransplantation Proceedings
Issue number2
Publication statusPublished - Mar 1 2016

ASJC Scopus subject areas

  • Surgery
  • Transplantation


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