TY - JOUR
T1 - Lung-angiodysplasia and von Willebrand's disease in a family with Rendu-Osler disease. A case report
AU - Girola, Silvio Stefano
AU - Cusa, Chiara
AU - Di Giulio, Giuseppe
AU - Marti, Antonio
AU - Mazzone, Antonino
PY - 1996/12
Y1 - 1996/12
N2 - A young woman suffering from sideropenic anemia, bleeding disorders related to von Willebrand's disease and pulmonary vascular teleangectasies presented at our observation. Laboratory findings, genetic and hemostatic studies revealed platelet aggregation defect while in her father and grandfather lung angiodysplastic lesions without platelet aggregation defect. The association between bleeding disorders and pulmonary angiodysplasia has rarely presented in literature and deficiency of von Willebrand factor might increase the risk of bleeding in patients with coexisting angiodysplastic disease.
AB - A young woman suffering from sideropenic anemia, bleeding disorders related to von Willebrand's disease and pulmonary vascular teleangectasies presented at our observation. Laboratory findings, genetic and hemostatic studies revealed platelet aggregation defect while in her father and grandfather lung angiodysplastic lesions without platelet aggregation defect. The association between bleeding disorders and pulmonary angiodysplasia has rarely presented in literature and deficiency of von Willebrand factor might increase the risk of bleeding in patients with coexisting angiodysplastic disease.
KW - Pulmonary angiodysplasia
KW - Von Willebrand's disease
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M3 - Article
C2 - 9066252
AN - SCOPUS:0030342576
VL - 87
SP - 589
EP - 591
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 12
ER -