Lung cancer among firefighters: Smoking-adjusted risk estimates in a pooled analysis of case-control studies

Carolina Bigert, Per Gustavsson, Kurt Straif, Dirk Taeger, Beate Pesch, Benjamin Kendzia, Joachim Schüz, Isabelle Stücker, Florence Guida, Irene Brüske, Heinz Erich Wichmann, Angela C. Pesatori, Maria Teresa Landi, Neil Caporaso, Lap Ah Tse, Ignatius Tak Sun Yu, Jack Siemiatycki, Jérôme Lavoué, Lorenzo Richiardi, Dario MirabelliLorenzo Simonato, Karl Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardón, David Zaridze, John K. Field, Andrea'T Mannetje, Neil Pearce, John McLaughlin, Paul Demers, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Susan Peters, Roel Vermeulen, Hans Kromhout, Thomas Brüning, Ann C. Olsson

Research output: Contribution to journalArticlepeer-review


Objectives: The aim of this study was to explore lung cancer risk among firefighters, with adjustment for smoking. Methods: We used pooled information from the SYNERGY project including 14 case-control studies conducted in Europe, Canada, New Zealand, and China, with lifetime work histories and smoking habits for 14,748 cases of lung cancer and 17,543 controls. We estimated odds ratios by unconditional logistic regression with adjustment for smoking and having ever been employed in a job known to present an excess risk of lung cancer. Results: There was no increased lung cancer risk overall or by specific cell type among firefighters (n=190), neither before nor after smoking adjustment. We observed no significant exposure-response relationship in terms of work duration. Conclusions: We found no evidence of an excess lung cancer risk related to occupational exposure as a firefighter.

Original languageEnglish
Pages (from-to)1137-1143
Number of pages7
JournalJournal of Occupational and Environmental Medicine
Issue number11
Publication statusPublished - Nov 28 2016

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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