Lung cancer in young adults

W. Bourke, D. Milstein, R. Giura, M. Donghi, M. Luisetti, A. H E Rubin, L. J. Smith

Research output: Contribution to journalArticle


Objective: To define the basis for the conflicting reports on the prognosis of lung cancer in young adults. Design: Retrospective review of lung cancer patients between 1977 and 1988. Setting: Medical centers in Chicago (Northwestern Memorial Hospital), northern Israel (Rambam Medical Center), and northern Italy (S. Anna and U. of Pavia Hospitals). Patients: Patients were ≤45 years of age with a diagnosis of primary lung cancer identified from tumor registry records, pathology reports, and hospital charts, plus a sample of patients >45 years of age. Measurements and Main Results: In Chicago, younger patients had a higher incidence of chest pain, fever, and neurologic symptoms at presentation than the older patients, and fewer were asymptomatic. They also had more lower lobe lesions on chest roentgenogram, a higher incidence of adenocarcinoma, more advanced disease, an increased likelihood of receiving chemotherapy, and reduced survival (p

Original languageEnglish
Pages (from-to)1723-1729
Number of pages7
Issue number6
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Bourke, W., Milstein, D., Giura, R., Donghi, M., Luisetti, M., Rubin, A. H. E., & Smith, L. J. (1992). Lung cancer in young adults. Chest, 102(6), 1723-1729.